Schistosoma haematobium
The parasite you're referring to is Schistosoma haematobium, which causes urogenital schistosomiasis and is characterized by eggs with a terminal spine that can become embedded in the bladder and urethral tissues. 1, 2
Parasite Characteristics and Mechanism
S. haematobium is a blood fluke (trematode) that specifically infects the genitourinary system, distinguishing it from other Schistosoma species. 2
The eggs of S. haematobium possess a terminal spine (a barb-like projection at one end) that facilitates their embedding into the bladder wall and urethral tissues, causing the characteristic tissue damage and symptoms. 2
These eggs become trapped in the bladder wall and urethral mucosa, where they elicit chronic immune-mediated inflammatory responses and granuloma formation. 2, 3
Geographic Distribution and Transmission
This parasite is endemic to Africa and the Middle East, though cases are increasingly seen elsewhere due to travel and immigration. 2, 4
Transmission occurs through exposure to freshwater containing cercariae released by infected freshwater snails. 5, 4
Clinical Presentation
Classic urogenital symptoms include hematuria (blood in urine), dysuria (painful urination), and hemospermia (blood in semen), typically appearing within 3 months of infection. 2
The condition can present with haematuria, proteinuria, dysuria, haematospermia, and inter-menstrual bleeding in women. 1
In acute infection (Katayama syndrome), patients may develop fever, urticarial rash, and marked eosinophilia 2-8 weeks after freshwater exposure. 1
Diagnostic Pitfalls
Misdiagnosis is common in non-endemic areas, with cases mistaken for ureteral calculus, bladder cancer, or eosinophilic cystitis. 4
Definitive diagnosis requires detection of parasite ova on microscopic urinalysis of terminal urine, though serology can be helpful when egg detection is negative. 1, 2
Fine ureteral calcifications appearing as parallel lines on imaging are considered pathognomonic of early-stage schistosomiasis. 2
Treatment
Praziquantel 40 mg/kg as a single oral dose is the first-line treatment for all S. haematobium infections. 6
Treatment is highly effective when administered promptly after diagnosis. 5