Is annual Hemoglobin A1C (HbA1c) monitoring still recommended for comfort care patients?

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Last updated: December 18, 2025View editorial policy

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A1C Monitoring in Comfort Care Patients

No, annual A1C monitoring is not recommended for comfort care patients, as this testing does not align with comfort-focused goals and provides no meaningful benefit to quality of life or symptom management in this population.

Rationale for Discontinuing A1C Testing

The American Diabetes Association guidelines recommend A1C testing at least twice yearly for patients meeting treatment goals, with the explicit purpose of guiding treatment adjustments to prevent long-term complications 1. However, these recommendations are designed for patients pursuing disease-modifying care, not comfort-focused care where the goal is symptom management and quality of life rather than prevention of future complications 1.

Why A1C Testing Is Not Appropriate for Comfort Care

  • A1C reflects average glycemia over 2-3 months and is strongly linked to long-term diabetes complications, making it a tool specifically designed for preventing microvascular and macrovascular complications that develop over years 1.

  • Comfort care patients have limited life expectancy where the prevention of long-term complications (retinopathy, nephropathy, neuropathy) is not a relevant treatment goal 1.

  • The test provides no information about immediate symptom burden such as symptomatic hyperglycemia or hypoglycemia, which are the primary glycemic concerns in comfort care 1.

  • Testing frequency recommendations assume active treatment modification to achieve specific glycemic targets, which contradicts the comfort care philosophy of avoiding burdensome interventions 1.

Alternative Approach to Glycemic Management in Comfort Care

Focus on symptom-based management rather than laboratory-driven targets:

  • Monitor for symptomatic hyperglycemia (polyuria, polydipsia, fatigue) and symptomatic hypoglycemia (confusion, tremor, diaphoresis) through clinical assessment rather than routine laboratory testing 1.

  • Use point-of-care glucose monitoring only when symptoms suggest problematic glycemic excursions that are affecting quality of life 1.

  • Simplify diabetes regimens to minimize hypoglycemia risk and treatment burden, which may include discontinuing medications with high hypoglycemia risk or those requiring frequent monitoring 1.

Common Pitfalls to Avoid

  • Do not continue routine A1C testing simply because "it's always been done" - this represents low-value care that does not serve the patient's comfort-focused goals 1.

  • Avoid tight glycemic control targets (A1C <7%) in comfort care patients, as these increase hypoglycemia risk and treatment burden without providing meaningful benefit given limited life expectancy 1.

  • Do not use A1C results to intensify therapy in comfort care patients, as this contradicts the fundamental principle of minimizing treatment burden 1.

  • Recognize that the 3-month timeframe for A1C assessment assumes patients will live long enough to benefit from complication prevention, which is not applicable to comfort care 1.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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