Treatment for Scalp Seborrheic Dermatitis
For scalp seborrheic dermatitis, start with topical antifungal shampoos (ketoconazole 2% or selenium sulfide 1%) as first-line therapy, reserving short-term topical corticosteroids for significant inflammation. 1, 2, 3
First-Line Antifungal Therapy
The most effective treatment combines antifungal medications to reduce Malassezia yeast with anti-inflammatory agents when needed 2. For scalp involvement specifically:
- Apply ketoconazole 2% cream or shampoo twice daily for 4 weeks until clinical clearing occurs 3, 4
- Alternative antifungal options include selenium sulfide 1% shampoo, pyrithione zinc shampoo, or ciclopirox shampoo 2, 5
- These formulations (shampoos, gels, solutions, foams) are preferred over ointments and creams because hair makes traditional formulations messy and difficult to use 6
Short-Term Corticosteroid Use for Inflammation
When significant erythema and inflammation are present:
- Use clobetasol propionate 0.05% shampoo for short periods only to avoid side effects including skin atrophy, telangiectasia, and tachyphylaxis 1, 7, 8
- Limit corticosteroid use to 2-4 weeks maximum, especially on the scalp where prolonged use carries risks 2
- Lower-potency options like hydrocortisone 1% can be considered for milder inflammation 2
Adjunctive Keratolytic Therapy
For thick, adherent scale:
- Coal tar preparations (1% strength preferred) can reduce inflammation and scaling, available in shampoo formulations 1, 2, 9
- Be aware that coal tar may cause folliculitis, irritation, and staining of skin and clothing 1
Critical Treatment Principles
Avoid these common pitfalls:
- Do not use topical corticosteroids long-term due to risk of skin atrophy and tachyphylaxis 1, 2
- Avoid alcohol-containing preparations as they increase skin dryness 2
- Watch for signs of contact dermatitis from topical preparations 1
- Monitor for secondary bacterial infection (crusting, weeping) which requires antibiotic treatment 1, 2
Supportive Skin Care Measures
- Apply emollients after bathing to provide a surface lipid film that retards water loss 1, 2
- Use mild, pH-neutral (pH 5) non-soap cleansers with tepid water rather than hot water 2
- Pat skin dry rather than rubbing 2