From the Research
Target Blood Pressure for New Lung Transplant Recipients
There are no direct studies on the target blood pressure for new lung transplant recipients. However, studies on kidney transplant recipients and hypertension management can provide some insights:
- The target blood pressure for kidney transplant recipients is generally considered to be less than or equal to 130/80 mmHg 1, 2, 3
- Achieving this target blood pressure can help minimize cardiovascular morbidity and reduce the risk of graft loss 1, 3
- Factors such as diabetes, heart disease, and albumin:creatinine ratio can affect blood pressure control in transplant recipients 2
- The selection of antihypertensive agents should be based on the patient's co-morbidities, with calcium channel blockers and renin-angiotensin-aldosterone system inhibitors being potential options 1, 3
Key Considerations
- Hypertension is a common issue in transplant recipients, affecting up to 80-90% of kidney transplant patients 3
- Effective blood pressure management is crucial to reduce the risk of graft loss and improve survival 1, 3
- Further research is needed to determine the optimal blood pressure targets and therapies for lung transplant recipients, as current evidence is largely based on kidney transplant studies 1
Relevant Findings
- A study on lung transplant recipients found that orthostatic blood pressure dysregulation is prevalent, but the use of antihypertensive medications did not elevate the risk of orthostatic hypotension 4
- Another study on pulmonary arterial hypertension patients undergoing lung transplant found that female sex and less severe tricuspid regurgitation were independently associated with better long-term survival 5