What are the small white bumps on the eyelids, possibly milia (small keratin-filled cysts)?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: April 7, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Differential Diagnosis for White Small Bumps on Eyelids

  • Single most likely diagnosis
    • Milia: These are small, white, keratin-filled cysts that often appear on the eyelids. They are very common and usually harmless, making them the most likely diagnosis for white small bumps on the eyelids.
  • Other Likely diagnoses
    • Chalazia: These are small bumps on the eyelid due to a blocked oil gland. They can appear white or flesh-colored and are often tender.
    • Xanthelasma: These are small, yellowish or white bumps on the eyelids caused by accumulation of fat under the skin. They are more common in people with high cholesterol.
    • Papillomas: These are benign growths that can appear as small, white bumps on the eyelids.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Basal cell carcinoma: Although rare, basal cell carcinoma can present as a small, white bump on the eyelid. It's crucial to rule out this diagnosis due to its potential for malignancy.
    • Squamous cell carcinoma: Similar to basal cell carcinoma, squamous cell carcinoma is a type of skin cancer that can appear on the eyelids and must not be missed.
  • Rare diagnoses
    • Sarcoidosis: This is a condition that can cause small bumps or nodules on the eyelids, among other symptoms. It's an autoimmune disease that can affect various parts of the body.
    • Syphilis: In its secondary stage, syphilis can cause a variety of skin symptoms, including small bumps on the eyelids. Although rare, it's an important diagnosis to consider due to its potential for serious complications if left untreated.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.