What is the administration protocol for Venefer infusion 300mg weekly for three weeks?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: December 19, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Venofer (Iron Sucrose) Infusion Order Template

For iron deficiency anemia treatment, administer Venofer 300 mg intravenously weekly for three consecutive weeks, with each dose infused over 1.5 to 2 hours in 100-250 mL of 0.9% normal saline.

Complete Order for Infusion Center

Patient Information Section

  • Patient Name: _________________
  • Date of Birth: _________________
  • Medical Record Number: _________________
  • Diagnosis: Iron Deficiency Anemia (ICD-10: D50.9 or specify)
  • Ordering Physician: _________________
  • Contact Number: _________________

Medication Order

Drug: Venofer (Iron Sucrose Injection)

Dose: 300 mg IV per infusion 1, 2

Frequency: Once weekly for 3 weeks (total of 3 infusions) 1, 3

Schedule:

  • Week 1: Date ________
  • Week 2: Date ________ (7 days after first dose)
  • Week 3: Date ________ (7 days after second dose)

Administration Instructions

Preparation:

  • Dilute 300 mg Venofer in 100-250 mL of 0.9% Sodium Chloride Injection USP 1, 3
  • Do NOT use 5% Dextrose solution for dilution
  • Inspect solution for particulate matter before administration

Infusion Rate:

  • Administer over 1.5 to 2 hours 1
  • Do NOT administer as IV push or bolus

Route: Intravenous infusion only

Pre-Infusion Requirements

Vital Signs:

  • Obtain baseline vital signs before each infusion
  • Monitor blood pressure for orthostatic changes 1

Laboratory Monitoring:

  • Baseline: Complete blood count with hemoglobin, serum ferritin, transferrin saturation
  • Follow-up labs: Repeat CBC 14-15 days after completion of third dose 1, 2

Safety Monitoring During Infusion

Observe patient for:

  • Hypersensitivity reactions (hypotension, dyspnea, rash, pruritus)
  • Injection site reactions or pain 1
  • Monitor vital signs every 30 minutes during infusion

Emergency Equipment:

  • Ensure availability of resuscitation equipment and medications for anaphylaxis management

Post-Infusion Instructions

  • Monitor patient for 30 minutes after completion of each infusion
  • Document any adverse reactions
  • Patient may experience transient metallic taste during infusion

Expected Outcomes

  • Anticipated hemoglobin increase: 2.7-3.2 g/dL after completion of 3-week course 1
  • Clinical improvement in anemia symptoms expected within 2-3 weeks 2

Contraindications and Precautions

Do NOT administer if:

  • Known hypersensitivity to Venofer or any component
  • Evidence of iron overload
  • Anemia not caused by iron deficiency

Contact Information

For questions or adverse events, contact:

  • Ordering physician: _________________
  • Phone: _________________
  • After hours: _________________

Physician Signature

Physician Signature: _________________ Date: _________

Print Name: _________________

DEA/License Number: _________________

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.