From the FDA Drug Label
Hydrastis canadensis 1M Less than 10 -12 mg hydrastine, berberine alkaloids per pellet (**contains 0.443 mg of the active ingredient per pellet) The FDA drug label does not answer the question.
From the Research
Berberine is beneficial for managing various health conditions, including type 2 diabetes, hyperlipidemia, and hypertension, with a comparable therapeutic effect to conventional medications and no serious side effects, as evidenced by the most recent and highest quality study 1. The benefits of berberine are multifaceted, including:
- Lowering blood glucose levels in people with type 2 diabetes, with effects comparable to metformin 2
- Reducing cholesterol levels, particularly low-density lipoprotein (LDL) cholesterol and triglycerides, and raising high-density lipoprotein (HDL) cholesterol levels 3
- Promoting weight loss and improving metabolic health 4
- Exhibiting anti-inflammatory and antimicrobial properties, which may help protect against various diseases, including cancer and digestive, metabolic, cardiovascular, and neurological diseases 5
- Having neuroprotective effects, including antioxidative, antiapoptotic, and anti-ischemic properties 5 The typical dosage of berberine ranges from 900-1500 mg daily, divided into 2-3 doses taken with meals, with 500 mg three times daily before meals being common for blood sugar management 2. However, berberine may cause digestive side effects like diarrhea, constipation, and stomach pain, especially at higher doses, and may interact with certain medications, particularly those processed by the liver 2. It is essential to consult with a healthcare provider before taking berberine, especially if you have existing health conditions or take other medications, to ensure safe and effective use 1.