From the Research
Common Side Effects of Cefiderocol
- The most common adverse events with cefiderocol were gastrointestinal symptoms such as diarrhea, constipation, nausea, vomiting, or upper abdominal pain 1
- Cefiderocol was generally well tolerated, with fewer side effects 2
- Cefiderocol demonstrates a favorable side effect profile 3
Common Side Effects of Doripenem/Sulbactam Therapy
- There is no direct information available on the common side effects of doripenem/sulbactam therapy in the provided studies
- However, sulbactam-durlobactam, a similar combination, has been studied and shown to be effective against certain bacterial pathogens, but its side effects are not explicitly mentioned in the provided studies 4, 5
Comparison of Side Effects
- Cefiderocol has been shown to have a better safety profile compared to other treatments, such as colistin 4
- The use of cefiderocol should be limited to the treatment of complicated urinary tract infections (cUTIs) from Gram-negative bacteria, especially in patients who have limited or no alternative treatment options, due to higher all-cause mortality associated with its use in other contexts 1