Do you write a History of Present Illness (HPI)?

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Last updated: December 20, 2025View editorial policy

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Writing the History of Present Illness (HPI)

Yes, clinicians should write a comprehensive History of Present Illness as it is the cornerstone of medical diagnosis and can identify up to 80% of medical conditions when done thoroughly. 1, 2

Core Purpose and Structure

The HPI serves as the foundation of diagnostic reasoning and must be systematically documented for every patient encounter. 1 The interview should begin with an open-ended question asking patients to describe their chief concern in their own words, then integrate relevant information from chart review to establish a complete clinical picture. 1, 3

Essential Components to Document

Begin with the patient's narrative, then systematically capture:

  • Primary symptoms: Onset, frequency, tempo, nature of change over time, and temporal relationships between events 1, 4
  • Functional impact: Effects on basic activities of daily living (bathing, dressing, eating, toileting, transferring) and instrumental activities (managing finances, medications, transportation, shopping, meal preparation, housework) 1, 4
  • Associated symptoms: All relevant symptom domains including cognition, mood, anxiety, and pertinent negatives (important symptoms that are absent) 5
  • Prior treatments: Previous therapies attempted and their outcomes, including medication adherence, side effects, and response 5, 4
  • Comprehensive medication list: All prescription drugs, over-the-counter medications, supplements, herbal remedies, and allergies 5, 4

Integrating Chart Review Information

Chart review should complement, not replace, direct patient interview. 3 Include prior diagnostic findings, previous treatment outcomes, and documented objective findings that patients may not recall, but clearly distinguish between information obtained directly from the patient versus from documentation. 5, 3 This approach reduces the likelihood of missing important historical details while avoiding perpetuation of previous diagnostic errors. 3

Critical Pitfall to Avoid

Overreliance on chart review can perpetuate diagnostic errors—always verify key elements directly with the patient. 5, 3 Allow patients to tell their story in their own words before integrating chart review information, or they may feel their narrative is being ignored. 3, 4

Informant Interview

Always seek an informant (care partner, family member) when possible, particularly for patients with cognitive or behavioral concerns. 1, 4 Informant reports provide added value beyond patient history alone and are essential when diminished insight accompanies the presenting condition. 1 Document the informant's relationship to patient, length of relationship, amount and type of contact, and their own demographic details. 4

Disease-Specific and Risk Factor Assessment

Systematically document:

  • Cardiovascular risk factors: History of myocardial infarction, arrhythmia, heart failure, angina, peripheral artery disease, hypertension, diabetes, and lipid measurements 1, 4
  • Family history: First-degree relatives with relevant conditions, including age at onset and age at death 4
  • Environmental and occupational exposures: Use structured questionnaires adapted to regional geography, workplace exposures, home environment, animal contact, and travel history 1, 4
  • Social determinants of health: Food insecurity, housing stability, transportation access, financial barriers, social support networks, tobacco/alcohol/substance use 5, 4

Preventive Care and Screening

Document vaccination status, cancer screening status, sexually transmitted disease screening if indicated, and results of depression/anxiety screening. 5 For elderly patients, include cognitive and functional performance assessments. 5

Organizational Best Practices

Structure the HPI chronologically, sequencing both relevant historical risks and known medical events to improve diagnostic reasoning. 5 Synthesize information from patient interview, informant reports, and prior documentation into a coherent narrative that supports clinical reasoning. 3 Cross-reference information from multiple sources to verify key historical elements. 5

Quality and Efficiency Considerations

Computer-generated HPIs using structured symptom collection algorithms have been shown to produce higher quality documentation than physician-written notes—scoring better on completeness, organization, usefulness, and comprehensibility. 6, 7 However, the artful elicitation of the HPI remains "an interactive exercise in spontaneity, unexpected responses, and nimble redirection" that requires clinical judgment. 1

Avoid making the HPI unwieldy with excessive chart review details—be selective and include only information relevant to the current presentation. 5 Document the rationale for treatment decisions to support the clinical reasoning process. 5

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Incorporating Chart Review Information into the History of Present Illness

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Conducting a Comprehensive History of Present Illness Interview

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Comprehensive History of Present Illness Guidelines

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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