What should be recorded as the primary cause of death in a patient with a history of ischemic heart disease (IHD) who developed septicemia after coronary artery bypass grafting (CABG) and subsequently died from multiorgan failure?

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Last updated: December 20, 2025View editorial policy

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Primary Cause of Death: Septicemia

The primary cause of death should be recorded as septicemia (Option A), as this represents the proximate pathophysiological process that directly led to the patient's multiorgan failure and death. 1

Death Certificate Documentation Framework

The American Heart Association provides clear guidance on proper death certificate completion that distinguishes between the immediate/proximate cause of death versus underlying conditions:

  • Part I of the death certificate should list the causal chain: multiorgan failure (immediate cause) due to septicemia (antecedent cause) due to surgical site infection post-CABG, following the proper sequence recommended by the American Heart Association 1

  • Part II should list ischemic heart disease as a contributing condition rather than the primary cause, since it was the underlying disease that necessitated surgery but did not directly cause death 1

Rationale Based on ACC/AHA Classification

The American College of Cardiology/American Heart Association guidelines explicitly categorize deaths by physiological system and list "Infection" as a distinct primary cause of death category, separate from cardiovascular causes:

  • The proximate cause—the pathophysiological process that directly led to death—is clearly the infectious process and resulting septicemia, not the pre-existing cardiac condition 1

  • The guidelines emphasize listing the specific condition that led to death rather than generic terms or underlying chronic conditions 1

Clinical Context Supporting This Determination

  • Septicemia following cardiac surgery carries mortality rates of 20-50% depending on severity, with early deaths from septic shock primarily attributable to intractable multiorgan failure related to the primary infection 1

  • In this case, the patient developed a clear temporal sequence: surgical site infection → septicemia → multiorgan failure → death, establishing septicemia as the direct cause 1

Common Pitfalls to Avoid

  • Do not list CABG (Option D) as the cause of death—it is a procedure, not a disease process, though it should be mentioned as context in Part I (surgical site infection post-CABG) 1

  • Do not list ischemic heart disease (Option B) as the primary cause—while it was the underlying condition requiring surgery, it did not directly cause this patient's death 1

  • Do not list congestive heart failure (Option C)—there is no indication this was the terminal event, and the ACC recommends avoiding listing "Heart Failure" as the underlying cause of death as it affects the quality of vital statistics 2

  • Avoid the common error of listing chronic conditions as the primary cause when an acute process directly caused death 1

References

Guideline

Primary Cause of Death: Septicemia

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Sudden Cardiac Death in Patients with Hypertension and Coronary Artery Disease

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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