Non-Opioid Pain Medicine Starting with "J"
Based on the evidence provided, there is no new non-opioid pain medicine starting with the letter "J" identified in the current medical literature or guidelines. The medications mentioned in the evidence that begin with "J" are not new non-opioid analgesics.
Medications Starting with "J" in Pain Management
The only pain-related medication starting with "J" found in the evidence is:
- Ketamine - This is an NMDA receptor antagonist that has been used for decades, not a new medication 1
- Ketamine is used by specialists in palliative care, pain management, and emergency medicine for refractory pain 1
- It carries risks of serious adverse effects including psychotomimetic experiences and hypertension, which constrain its broader use 1
- Ketamine is not classified as a non-opioid analgesic in the traditional sense—it is an anesthetic agent used at subanesthetic doses for pain 1
Common Non-Opioid Analgesics Available
If you are seeking non-opioid pain management options, the evidence-based first-line agents include:
- Acetaminophen (paracetamol) - for mild to moderate pain 1, 2
- NSAIDs (diclofenac, ketoprofen, ibuprofen, naproxen) - for inflammatory and musculoskeletal pain 1
- Gabapentinoids (gabapentin, pregabalin) - for neuropathic pain 1
- Topical agents (lidocaine patches, capsaicin) - for localized pain with high safety profile 1
Emerging Non-Opioid Therapies
Recent developments in non-opioid pain management include:
- Nerve growth factor (NGF) monoclonal antibodies 3
- TRPV1 antagonists 3
- Selective sodium channel blockers 3
None of these emerging therapies start with the letter "J."