What are the guidelines for monitored anesthesia care?

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Last updated: December 21, 2025View editorial policy

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Monitored Anesthesia Care Guidelines

Core Definition and Requirements

Monitored anesthesia care (MAC) is a planned procedure requiring continuous presence of an appropriately trained anesthesia provider with standard monitoring including pulse oximetry, non-invasive blood pressure, ECG, and capnography whenever there is loss of response to verbal contact. 1

Minimum Monitoring Standards

The Association of Anaesthetists establishes these as essential minimum monitoring for all MAC procedures, regardless of duration or location: 1

  • Pulse oximeter with plethysmograph 1
  • Non-invasive blood pressure (NIBP) 1
  • ECG monitoring 1
  • Temperature (before procedure and every 30 minutes) 1
  • Waveform capnography (mandatory whenever loss of response to verbal contact occurs) 1

Critical Monitoring Caveat

Capnography must be used during procedural sedation whenever there is loss of response to verbal contact. 1 This is non-negotiable as it provides early detection of respiratory depression and hypoventilation. 2

Personnel Requirements

An appropriately trained and experienced anesthesia provider must be present continuously throughout the entire procedure to ensure patient safety. 2 This continuous presence is mandatory and cannot be delegated during the actual sedation period. 2

Sedation Administration Protocol

Initiation Phase

For MAC sedation initiation, use either: 3

  • Infusion method: Propofol 100-150 mcg/kg/min for 3-5 minutes, titrated to effect 3
  • Slow injection method: Propofol approximately 0.5 mg/kg administered over 3-5 minutes 3

Critical warning: Rapid bolus administration must never be used, especially in elderly, debilitated, or ASA-PS III-IV patients, as this causes dangerous cardiorespiratory depression including hypotension, apnea, airway obstruction, and oxygen desaturation. 3

Maintenance Phase

Variable rate infusion is strongly preferred over intermittent bolus dosing. 3 Typical maintenance rates: 3

  • Initial 10-15 minutes: 25-75 mcg/kg/min (1.5-4.5 mg/kg/h) 3
  • Subsequently: Decrease to 25-50 mcg/kg/min, adjusted to clinical response 3
  • Allow approximately 2 minutes for peak drug effect when titrating 3

Always titrate downward in the absence of light sedation signs until mild responses to stimulation are obtained to avoid excessive sedation. 3

Special Population Adjustments

Elderly, Debilitated, or ASA-PS III-IV Patients

  • Reduce propofol dosage to approximately 80% of usual adult dose 3
  • Administration must occur over 3-5 minutes minimum 3
  • Consider processed EEG monitoring to avoid excessive anesthetic depth 4
  • Never use rapid bolus techniques 3

Alarm Management

All alarm limits must be set to patient-specific values before use, and audible alarms must be enabled during the procedure. 1 The existing default alarm settings are frequently inappropriate and should be adjusted. 1

Departments should establish consensus-based alarm limits and standardize these across monitors to improve safety. 1

Documentation Requirements

Maintain an accurate anesthetic record with monitoring data documented at least every 5 minutes, including: 2

  • Heart rate, blood pressure, SpO2, and ETCO2 2
  • All medications with timing and dosages 2
  • Any complications and interventions 2

Electronic anesthetic record systems integrated into the hospital's electronic health record are strongly recommended. 1, 2

Equipment Preparation

The anesthesiologist must check all equipment before use and be familiar with its operation. 1 This includes: 1

  • Verifying infusion devices are functioning with alarms enabled 1
  • Ensuring IV cannula visibility throughout the procedure when practical 1
  • Confirming oxygen supply adequacy 1

Blood Glucose Monitoring

Capillary blood glucose monitoring must be immediately accessible in every location where MAC is performed. 1 For patients with treated diabetes: 1

  • Measure blood glucose before induction 1
  • Monitor at least hourly during the procedure 1
  • Target range: 6-10 mmol/L (upper limit of 12 mmol/L may be tolerated) 1

Recovery and Transfer Standards

Continue monitoring through recovery until the patient is fully responsive. 2 If transferring an anesthetized or sedated patient: 1

  • Maintain same monitoring standards as in the procedure location 1
  • Use capnography if any airway device remains in place 1
  • Ensure adequate oxygen supply for transfer duration 1

Common Pitfalls to Avoid

Airway obstruction risk: Have airway equipment immediately available and position patient to optimize airway access for emergency intervention. 2 Continuous monitoring of respiratory function is critical. 2

Inadequate regional block: If the regional block is inadequate, excessive sedation may be required, potentially negating MAC safety advantages. 4 MAC provides poor blockade of stress response unless the regional block provides profound anesthesia. 4

Fire safety: When electrocautery is used near the airway, configure surgical drapes to prevent oxygen accumulation, moisten sponges near ignition sources, and notify the surgeon when ignition sources are near oxygen-enriched atmospheres. 2

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Monitored Anesthesia Care Protocol for Neck Dissection

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Monitored Anesthesia Care for Shoulder Surgery

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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