From the Research
Optimal Peak Expiratory Flow (PEF) Numbers
The optimal PEF numbers vary depending on factors such as age, sex, and height. According to a study published in 2021 1, the mean PEF values were 367.10 and 253.00 L/min for men and women, respectively, in a middle-aged and elderly Chinese population.
Factors Affecting PEF
Several factors can affect PEF, including:
- Age: PEF decreases with age in both men and women 1
- Sex: Men tend to have higher PEF values than women 1
- Height and weight: These factors are positively associated with PEF 1
- Smoking status: Smoking is negatively associated with PEF 1
- Handgrip strength: This factor is positively associated with PEF 1
- Residence: Living in a rural area is positively associated with PEF 1
PEF in Asthma Diagnosis
PEF can be used as a diagnostic tool for asthma, particularly in low-resource settings. A study published in 2003 2 found that PEF measurements had a high specificity and negative predictive value for airway obstruction and bronchodilator response in children with asthma. Another study published in 2019 3 found that PEF had a sensitivity of 47% and a specificity of 87% for diagnosing asthma in adults.
PEF in COPD Exacerbation Prediction
PEF can also be used to predict COPD exacerbations. A study published in 2019 4 found that monitoring PEF could predict hospitalized exacerbations of COPD, with an optimal cutoff value of 28 L/min (17% from baseline) 24 hours before exacerbation.
Comparison of PEF Meters
Different PEF meters can produce varying results, and it is essential to compare their measurements to ensure accuracy. A study published in 2010 5 compared five portable PEF meters and found significant differences between their measurements and spirometric values.