What is Sculptra (Poly-L-lactic acid)?

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Last updated: April 8, 2025View editorial policy

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From the Research

Sculptra is a highly effective and safe dermal filler made of poly-L-lactic acid (PLLA) used for facial rejuvenation, providing gradual, long-lasting results that can last up to two years. The most recent and highest quality study 1 supports the use of Sculptra as a stimulatory filler that creates its effect through encouraging neocollagenesis when injected. This study highlights the unique considerations of Sculptra, including its biocompatibility, resorbability, and ability to stimulate collagen production.

Key Benefits of Sculptra

  • Provides gradual, long-lasting results that can last up to two years
  • Stimulates natural collagen production, addressing the underlying cause of facial aging
  • Minimally invasive procedure with little downtime
  • Can be used to restore volume loss in various areas, including deep facial wrinkles, nasolabial folds, temples, and cheeks

Treatment Details

  • Typically requires 2-3 sessions spaced about 4-6 weeks apart
  • Each session involves multiple small injections in the targeted areas
  • Patients may experience temporary swelling, bruising, or redness at injection sites
  • Results develop gradually over several months as collagen builds, creating a more natural-looking improvement in facial contours

Suitable Candidates

  • Those seeking subtle, progressive enhancement rather than immediate dramatic results
  • Individuals with facial lipoatrophy, including HIV-positive patients
  • Patients with deep facial wrinkles, nasolabial folds, temples, and cheeks who want to restore volume loss

Overall, Sculptra is a highly effective and safe treatment option for facial rejuvenation, providing long-lasting results and stimulating natural collagen production. As noted in the study by 1, Sculptra is a worthy inclusion in the first line of tools for cosmetic rejuvenation and reconstructive soft tissue deficits and lipoatrophy.

References

Research

Sculptra: a stimulatory filler.

Facial plastic surgery : FPS, 2009

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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