Which countries require the yellow fever vaccine for entry?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: December 22, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Yellow Fever Vaccine Country Requirements

Certain countries require proof of yellow fever vaccination for entry, particularly in sub-Saharan Africa and tropical South America, and travelers arriving without valid documentation may face quarantine for up to 6 days or denial of entry. 1

Mandatory Country Entry Requirements

The yellow fever vaccine is required by specific countries under the International Health Regulations (IHR), though these requirements differ from CDC medical recommendations. 1

Key points about country requirements:

  • Requirements are mandatory and intended primarily to prevent importation and transmission of yellow fever virus within a country. 1
  • Some countries require evidence of vaccination from all entering travelers, including those arriving directly from the United States. 1
  • Certain countries may require proof of vaccination even if you are only in transit and have visited any country thought to harbor yellow fever virus. 1
  • Some countries do not require vaccination for infants younger than specific ages (e.g., <6 months, <9 months, or <1 year, depending on the country). 1

Geographic Distribution of Requirements

Endemic regions where vaccination is commonly required include:

  • Sub-Saharan Africa: Multiple countries in this region require proof of vaccination, particularly during travel to the "meningitis belt" during dry season (December-June). 2
  • Tropical South America: Countries in this region, including Brazil, Colombia, and Peru, have requirements based on endemic transmission risk. 2, 3
  • Trinidad: Specifically for travel to forested areas. 2

Documentation Requirements

You must obtain proper documentation to satisfy country entry requirements:

  • Yellow fever vaccines must be administered at an approved Yellow Fever Vaccination Center in the United States, designated by state and territorial health departments. 1
  • You must possess a completed International Certificate of Vaccination or Prophylaxis (ICVP), validated with the provider's signature and official yellow fever vaccination center stamp. 1
  • The certificate is valid beginning 10 days after vaccination and extends for 10 years. 1
  • An incomplete or inaccurate ICVP is not valid and can result in quarantine, denied entry, or forced revaccination at the point of entry. 1

Medical Waivers

If vaccination is medically contraindicated, a physician may issue a waiver by completing the "Medical Contraindications to Vaccination" section of the ICVP with a signed, dated letter on letterhead stationery bearing the official yellow fever vaccination stamp. 1, 2 However, be aware that destination countries may not accept the medical waiver, and travelers should be informed of increased infection risk. 1

Critical Timing Considerations

  • Vaccination must be received at least 10 days before travel to ensure immunity and for the certificate to be valid. 2, 4
  • When a booster dose is administered within the 10-year validity period, the certificate is considered valid from the day of the most recent vaccination. 1
  • Starting vaccinations 4-6 weeks before departure is recommended to ensure adequate time for all necessary doses. 5

Common Pitfalls to Avoid

  • Insufficient lead time: Approximately 21.7% of travelers fail to comply with the 10-day advance vaccination requirement, with last-minute decisions being the most common reason. 6
  • Incomplete documentation: Failure to secure proper validation with official stamps can cause serious travel disruptions. 1
  • Assuming transit exemptions: Some countries require proof even for travelers only passing through. 1

Where to Find Current Requirements

Because country requirements change frequently, travelers should obtain updated information before each trip from the CDC travel website (http://wwwnc.cdc.gov/travel) or state/local health departments. 1 The specific list of countries requiring yellow fever vaccination is maintained and updated regularly by the CDC. 1

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Yellow Fever Vaccination Guidelines

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Yellow fever vaccine: an effective vaccine for travelers.

Human vaccines & immunotherapeutics, 2014

Guideline

Yellow Fever Prevention and Treatment

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Pre-Travel Vaccinations for Developing Countries

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.