What does a serum sodium level of 141 and an Antidiuretic Hormone (ADH) level of 0.8 indicate, and how should it be managed?

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Last updated: December 22, 2025View editorial policy

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Your Lab Values Are Normal

Your serum sodium of 141 mmol/L and ADH of 0.8 pg/mL are both within normal ranges and require no intervention. 1

Understanding Your Results

Serum Sodium Level

  • Normal range: 135-145 mmol/L 1
  • Your value of 141 mmol/L falls comfortably in the middle of this range
  • This indicates proper water balance and normal kidney function 2

ADH (Antidiuretic Hormone) Level

  • Normal range: 0.0-4.7 pg/mL 1
  • Your value of 0.8 pg/mL is appropriately low-normal
  • This level is consistent with your normal sodium concentration 3

What This Means Physiologically

Your body's water regulation system is functioning properly. 4

  • With normal serum sodium, your osmoreceptors are not triggering excessive ADH release 3
  • The low-normal ADH level (0.8) indicates your kidneys are appropriately excreting free water without excessive retention 5
  • This represents normal osmoregulation—your thirst mechanism and ADH secretion are working in harmony 4, 3

No Action Required

You do not need:

  • Fluid restriction 1
  • Sodium supplementation 1
  • Any medication adjustments 1
  • Further workup for sodium disorders 2

When to Seek Medical Attention

Contact your physician if you develop:

  • Symptoms of hyponatremia: nausea, headache, confusion, weakness, or seizures (sodium <135 mmol/L) 2
  • Symptoms of hypernatremia: excessive thirst, confusion, or altered mental status (sodium >145 mmol/L) 2, 6
  • Significant changes in urination patterns 3

Your results indicate normal water and electrolyte homeostasis with no evidence of SIADH, diabetes insipidus, or any other disorder of water metabolism. 5, 3

References

Guideline

Management of Sodium Imbalance

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

[Pathophysiology of dehydration].

Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1993

Research

[Hyponatremia--with comments on hypernatremia].

Therapeutische Umschau. Revue therapeutique, 2000

Research

Dehydration, Hypernatremia, and Hyponatremia.

Clinics in geriatric medicine, 2015

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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