Differential Diagnosis for a 31-year-old Male with Penile Discomfort, Irritation, and Unusual Discharge
- Single most likely diagnosis:
- Urethritis: This condition, often caused by sexually transmitted infections (STIs) like gonorrhea or chlamydia, is characterized by inflammation of the urethra, leading to symptoms such as discharge, irritation, and discomfort. The patient's age and symptoms align closely with this diagnosis.
- Other Likely diagnoses:
- Balanitis: An inflammation of the glans penis, which can be caused by poor hygiene, infections (including STIs), or allergic reactions. Symptoms include redness, itching, and discharge.
- Phimosis: A condition where the foreskin cannot be fully retracted over the glans penis, which can lead to irritation, discomfort, and potentially an increased risk of infections.
- Yeast Infection (Candidiasis): Can cause irritation, redness, and a white discharge on the penis, often associated with diabetes, poor hygiene, or antibiotic use.
- Do Not Miss (ddxs that may not be likely, but would be deadly if missed):
- Penile Cancer: Although rare, any unusual or persistent symptoms should prompt consideration of penile cancer, especially in uncircumcised men or those with a history of HPV infection.
- Syphilis: A sexually transmitted infection that can cause a wide range of symptoms, including genital ulcers, rash, and eventually serious complications if left untreated.
- Rare diagnoses:
- Lichen Sclerosus: A chronic inflammatory skin condition that can affect the genital area, causing itching, pain, and scarring.
- Psoriasis: An autoimmune condition that can cause red, scaly patches on the skin, including the genital area, leading to discomfort and irritation.
- Fixed Drug Eruption: A condition caused by an adverse reaction to medication, resulting in skin lesions that recur at the same site each time the drug is taken.