Why do some surgeons prefer one-lung anesthesia (OLA) for off-pump coronary artery bypass (OPCAB) via median sternotomy approach?

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Last updated: December 23, 2025View editorial policy

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One-Lung Anesthesia for OPCAB via Median Sternotomy

Some surgeons prefer one-lung anesthesia (OLA) during median sternotomy OPCAB primarily to improve surgical exposure and facilitate hemostasis, though this practice is not standard and remains surgeon-specific rather than guideline-recommended.

Primary Rationale for OLA in Sternotomy OPCAB

The use of single-lung ventilation in median sternotomy OPCAB is not a standard requirement but rather a technique preference among certain surgeons. The evidence base for this practice comes primarily from minimally invasive cardiac surgery literature rather than conventional sternotomy OPCAB guidelines.

Surgical Exposure Benefits

  • Single-lung ventilation can facilitate identification of anatomic landmarks before initiating cardiopulmonary bypass, particularly useful in reoperative cases where lung adhesions need division 1
  • Deflating the right lung improves visualization of cardiac structures and provides "straight-on" access to surgical targets, though this benefit is more pronounced in thoracotomy approaches than sternotomy 1
  • Hemostasis is significantly facilitated at the end of the procedure with the lung deflated, allowing better visualization of bleeding points 1

Technical Considerations

The decision to use OLA in sternotomy OPCAB appears to be experience-dependent and surgeon-specific rather than evidence-based:

  • Some experienced surgeons prefer not to use single-lung ventilation even in minimally invasive approaches, accepting increased CPB times as a trade-off 1
  • Anesthetic management for OPCAB requires standardization according to guidelines, but specific ventilation strategies are not mandated 1
  • The technique comes at the expense of increased operative complexity without clear outcome benefits in the sternotomy approach 1

Important Caveats and Contraindications

Physiologic Tolerance Issues

  • Not all patients tolerate single-lung ventilation, with persistent oxygen desaturation occurring in some cases requiring conversion to double-lung ventilation 2
  • Patients with higher BMI, higher STS scores, and more extensive coronary disease are more likely to be intolerant of single-lung ventilation 2
  • Intolerance of single-lung ventilation does not preclude successful OPCAB, as double-lung ventilation remains feasible with similar outcomes 2

Lack of Guideline Support

No major cardiac surgery guidelines specifically recommend OLA for conventional median sternotomy OPCAB 1, 3. The guidelines emphasize:

  • Standardization of anesthetic techniques for OPCAB is needed but specific ventilation strategies are not prescribed 1
  • Off-pump CABG should only be performed by surgeons with extensive experience given technical complexity, but ventilation strategy is not addressed 3
  • The primary focus remains on avoiding aortic manipulation rather than ventilation strategy for reducing complications 1, 3

Clinical Bottom Line

The use of OLA in median sternotomy OPCAB represents individual surgeon preference rather than evidence-based practice. The technique may offer marginal improvements in surgical field visualization and hemostasis but:

  • Adds anesthetic complexity without demonstrated outcome benefits in the sternotomy approach 1, 2
  • May not be tolerated by all patients, particularly those with higher risk profiles 2
  • Is not mentioned or recommended in major CABG guidelines as a standard technique 1, 3

For conventional median sternotomy OPCAB, standard two-lung ventilation remains appropriate for most patients, with OLA reserved for specific surgeon preference or anatomic considerations rather than routine practice 1, 2.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Off-Pump Coronary Artery Bypass Grafting

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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