Differential Diagnosis for Labial Agglutination in an 82-Year-Old Woman
Single Most Likely Diagnosis
- Lichen planus: This is a chronic inflammatory condition that can cause labial agglutination, especially in postmenopausal women. The condition is characterized by purplish, itchy, flat bumps on the skin and mucous membranes, which can lead to adhesions.
Other Likely Diagnoses
- Lichen sclerosis: This condition can cause thinning and scarring of the vulvar skin, leading to labial agglutination. It is more common in postmenopausal women and can be asymptomatic or cause itching and discomfort.
- Vulvar atrophy: This condition is caused by a decrease in estrogen levels, which can lead to thinning and drying of the vulvar skin, resulting in labial agglutination. It is common in postmenopausal women.
Do Not Miss Diagnoses
- Cancer: Although less likely, it is crucial to rule out vulvar cancer, as it can present with labial agglutination. A biopsy would be necessary to confirm the diagnosis.
- Infections: Certain infections, such as genital herpes or syphilis, can cause labial agglutination. These conditions require prompt treatment to prevent complications.
Rare Diagnoses
- Behçet's disease: This rare condition is characterized by recurrent oral and genital ulcers, which can lead to labial agglutination. It is more common in younger women but can occur in older adults.
- Stevens-Johnson syndrome: This rare condition is a severe skin and mucous membrane disorder that can cause labial agglutination. It is often triggered by medications or infections.