Recommended Rapid Mood Screener for Adolescents
The PHQ-9 Modified for Adolescents is the recommended rapid mood screener for adolescents aged 12-18 years, with an optimal cutoff score of 11 demonstrating sensitivity of 89.5% and specificity of 77.5%. 1, 2, 3
Primary Screening Tool
The Patient Health Questionnaire-9 (PHQ-9) Modified for Adolescents stands as the most extensively validated and recommended depression screening instrument for this age group. 1, 2 This tool:
- Includes all nine DSM criteria for depression, with each item scored 0-3 based on symptom frequency over the past two weeks 1
- Takes 3-5 minutes to complete and is suitable for self-administration 1
- Has been validated specifically in adolescent primary care populations aged 12-18 years 1, 4, 3
- Demonstrates superior performance compared to the PHQ-2 brief screener, with significantly higher specificity (86.5% vs 79.4%) 4
The Patient Health Questionnaire for Adolescents (PHQ-A) represents an alternative with the highest positive predictive value among adolescent screening tools (sensitivity 73%, specificity 94%), though it has been less extensively studied than the PHQ-9. 5, 2
Optimal Cutoff Score and Interpretation
Use a cutoff score of 11 for the PHQ-9 in adolescents, which maximizes sensitivity without loss of specificity. 1, 3 This cutoff is higher than the traditional adult threshold of 10 and has been validated across multiple studies. 4, 6, 3
The receiver-operator-curve analysis confirms an area under the curve of 0.88, indicating excellent discriminatory power. 3
Age-Specific Considerations
Universal screening should begin at age 12 years and continue through age 18 years. 1, 2, 7 The evidence base strongly supports this age range:
- Most treatment efficacy trials for SSRIs and psychotherapy were restricted to adolescents aged 12-14 years or older 1
- No screening studies included children younger than age 11 years 5, 2, 7
- The USPSTF assigns an "I" statement (insufficient evidence) for depression screening in children aged 11 years or younger 7
- Mean age of onset for major depressive disorder is 14-15 years 1
Management Algorithm Based on Scores
PHQ-9 Score 1-7 (None/Mild):
- Provide education about depression and normal stress responses 1, 2
- Ensure adequate coping skills and access to resources 1, 2
- Consider reassessment at future visits 1, 2
PHQ-9 Score 8-14 (Moderate):
- Evaluate for pertinent history and specific risk factors for depression 1, 2
- Consider referral to psychology or psychiatry for diagnostic evaluation 1, 2
- Offer low-intensity intervention options 1
PHQ-9 Score 15-27 (Moderate to Severe/Severe):
- Make immediate referral to psychology and/or psychiatry for diagnosis and treatment 1, 2
- Assess for risk of harm to self or others 1, 2
- Evaluate for medical or substance-induced causes of depressive symptoms 1, 2
Critical Safety Considerations
Pay particular attention to item 9 of the PHQ-9, which assesses thoughts of self-harm—any positive response requires immediate referral regardless of total score. 1, 2 This is a critical safety measure that cannot be overlooked. 1, 2
Self-administered scales are particularly valuable because adolescents may disclose suicidality on self-report that they deny in person. 1
Common Pitfalls to Avoid
Never screen without having clear protocols for managing positive screens, as screening alone without intervention does not improve outcomes. 1, 2 This requires:
- Designated responsibilities among the clinical team 1
- Clear referral pathways to mental health specialists 1, 2
- Protocols for immediate safety assessment when item 9 is positive 1, 2
Recognize that irritability, not sadness, may be the primary manifestation of depression in adolescents—look for cranky mood, oppositional behavior, and loss of interest in previously enjoyed activities. 1, 2
Do not assume absence of suicidal ideation means low risk in patients with previous suicide attempts, as they remain at elevated risk if underlying factors remain unchanged. 1, 2
Alternative Brief Screening Option
The PHQ-2 (first two items of PHQ-9) can serve as an initial brief screen with a cutoff score of 3, demonstrating sensitivity of 73.7% and specificity of 75.2%. 1, 7 However, this two-stage approach may miss cases of suicidality that would be detected by the full PHQ-9, so the full PHQ-9 is preferred for comprehensive screening. 1, 4
Validation Across Populations
The PHQ-9 has demonstrated strong psychometric properties across diverse adolescent populations:
- Internal consistency (omega) of 0.87 in school-based samples 8
- Strong measurement invariance across gender 8
- Positive associations with anxiety symptoms, emotional/behavioral problems, and negative associations with prosocial behavior and quality of life 8
- Validated in both clinical and school settings 8, 6