How many Solostar (insulin glargine) pens are needed for a 30-day supply at a dose of 44 units daily?

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Insulin Glargine SoloStar Pen Supply Calculation

For a 30-day supply at 44 units daily, you will need 5 SoloStar pens.

Calculation Breakdown

  • Each SoloStar prefilled pen contains exactly 300 units of insulin glargine (3 mL of U-100 insulin) 1

  • At 44 units per day, one pen lasts: 300 units ÷ 44 units/day = 6.82 days per pen 2

  • For a 30-day supply: 30 days ÷ 6.82 days per pen = 4.4 pens 2

  • Rounding up to 5 pens ensures adequate supply and accounts for practical considerations 3

Why 5 Pens (Not 4)

  • The mathematical calculation yields 4.4 pens, but you cannot dispense a partial pen 2

  • Prescribing 5 pens provides a buffer for:

    • Insulin wastage during pen priming (required before each injection) 3, 1
    • Potential insulin remaining in the pen after the last deliverable dose 3
    • Premature needle withdrawal, which can result in 2.6-20.2% underdelivery depending on technique 4
    • Any doses that may be needed if blood glucose monitoring indicates additional correction doses 5

Total Units Provided

  • 5 pens × 300 units per pen = 1,500 units total 2
  • Daily requirement: 44 units × 30 days = 1,320 units needed 2
  • This provides a 180-unit buffer (approximately 4 days extra), which is appropriate for safe insulin management 3

Important Prescribing Considerations

  • SoloStar is a disposable prefilled pen that is discarded after all insulin is used 2, 1

  • Each pen can deliver doses from 1 to 80 units in 1-unit increments 1

  • Your 44-unit daily dose falls well within the single-injection capacity of the pen 1

  • Do not attempt to extract insulin from the pen with a syringe, as this will result in incorrect dosing 1

Cost Implications

  • At median pricing, U-100 glargine prefilled pens cost approximately $77-$109 per 1,000 units (AWP/NADAC) 6

  • For 1,500 units (5 pens), estimated monthly cost ranges from $116-$164 depending on whether branded or biosimilar products are used 6

  • Generic/biosimilar glargine pens may offer cost savings, with prices as low as $59-$74 per 1,000 units for some formulations 6

References

Guideline

Insulin Pen Requirements for Daily Dosage

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Insulin Pen Supply Calculation for Patients with Daily Insulin Injections

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Insulin Glargine Dosing and Administration

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

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Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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