Can a copper Intrauterine Device (IUD) cause thyroid issues?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: December 23, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Can a Copper IUD Cause Thyroid Issues?

No, there is no evidence that copper IUDs cause thyroid dysfunction or thyroid-related problems. The available medical guidelines and research do not identify thyroid issues as a recognized side effect or complication of copper IUD use.

What the Evidence Shows

Documented Side Effects of Copper IUDs

The established side effects of copper IUDs are well-characterized and do not include thyroid dysfunction:

  • Menstrual changes: Increased bleeding and pain during menses are the most common side effects, with most bleeding and pain complaints decreasing over time during the first year of use 1

  • Hematologic effects: Copper IUDs can cause decreased serum iron and reduced transferrin saturation, particularly with long-term use, though mean hemoglobin levels typically remain stable 2

  • Trace metal changes: Copper IUD use causes a slight elevation in serum copper levels (from 160.40 μg/dl at baseline to 170.22 μg/dl at 3 months), but these levels do not reach toxic ranges 3

  • Infection risk: The primary serious complication is pelvic inflammatory disease, which occurs mainly in the first 20-21 days after insertion, particularly in women with active STIs 4, 5

Contraindications Do Not Include Thyroid Disease

Major medical organizations have established clear contraindications for copper IUD use, and thyroid disorders are notably absent:

  • Absolute contraindications: Only pregnancy is listed as an absolute contraindication (Category 4) 6

  • Relative contraindications: Active STIs (chlamydia or gonorrhea) are Category 3 contraindications 6

  • No thyroid-related restrictions: Neither hypothyroidism nor hyperthyroidism appears in any medical eligibility criteria for copper IUD use 4, 6, 5

Clinical Implications

If a patient with a copper IUD develops thyroid symptoms, the IUD is not the cause and should not be removed for this indication. The thyroid issue requires standard evaluation and management independent of contraceptive choice. The copper IUD can safely remain in place during thyroid disease diagnosis and treatment, as there are no documented interactions between copper IUDs and thyroid function 4.

References

Research

Changes in copper and zinc serum levels in women wearing a copper TCu-380A intrauterine device.

The European journal of contraception & reproductive health care : the official journal of the European Society of Contraception, 2014

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Copper T IUD Contraindications and Risks

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Contraindications for the Use of Copper Intrauterine Devices

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.