What is the diagnosis for a patient with a history of esophageal ulceration at age 18, presenting with left upper quadrant (LUQ) pain and pressure under the sternum, feeling as if food is stuck in the esophagus, without chest burning?

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Differential Diagnosis

  • Single most likely diagnosis
    • Esophageal stricture: The patient's history of esophageal ulceration and current symptoms of food sticking in the esophagus suggest a possible stricture, which is a narrowing of the esophagus that can cause dysphagia.
  • Other Likely diagnoses
    • Gastroesophageal reflux disease (GERD): Although the patient denies burning in the chest, GERD can cause a variety of symptoms, including dysphagia and pressure under the sternum.
    • Esophageal dysmotility: The patient's symptoms of food sticking in the esophagus and pressure under the sternum could be related to abnormal esophageal motility.
    • Eosinophilic esophagitis: This condition can cause dysphagia, food impaction, and chest pain, and is more common in young adults.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Esophageal cancer: Although the patient is young, esophageal cancer can occur at any age, and a history of esophageal ulceration is a risk factor.
    • Achalasia: This rare condition can cause dysphagia, regurgitation, and chest pain, and can be associated with an increased risk of esophageal cancer.
  • Rare diagnoses
    • Esophageal ring or web: These are rare conditions that can cause dysphagia and food impaction.
    • Scleroderma: This autoimmune disease can cause esophageal dysmotility and dysphagia, although it is a rare condition.
    • Chagas disease: This parasitic infection can cause esophageal dysmotility and dysphagia, although it is rare in the United States.

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This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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