What is the maximum dose of magnesium glycinate (Mg(Gly)2) for a 6-year-old child?

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Maximum Dose of Magnesium Glycinate for a Six-Year-Old

For a 6-year-old child, the maximum daily dose of elemental magnesium (including magnesium glycinate) should not exceed 110-130 mg per day to minimize gastrointestinal side effects. 1

Recommended Dosing Framework

The American Academy of Pediatrics recommends a standard supplementation dose of approximately 5-6 mg/kg/day of elemental magnesium for children. 2, 1 For an average-weight 6-year-old (approximately 20-22 kg), this translates to:

  • Starting dose: 100-130 mg elemental magnesium daily 2, 1
  • Maximum safe dose: 110-130 mg elemental magnesium daily 1

Critical Formulation Consideration

Magnesium glycinate (bisglycinate) is preferred over other forms due to superior gastrointestinal tolerance. 2, 3 When calculating dosage, you must account for elemental magnesium content only—magnesium glycinate contains approximately 14-18% elemental magnesium by weight, so a 700-800 mg dose of magnesium glycinate provides roughly 100-130 mg of elemental magnesium. 2

Administration Guidelines

  • Timing: Administer 1-2 hours before bedtime if using for sleep support 2
  • Dose-limiting factor: Gastrointestinal effects (diarrhea, abdominal cramping) are the primary concern at higher doses 1, 3

Essential Safety Monitoring

Before initiating magnesium supplementation:

  • Assess renal function, as magnesium is primarily renally excreted and contraindicated in severe renal impairment 1, 3
  • Monitor for hypermagnesemia signs: muscle weakness, hypotension, or bradycardia 3
  • Watch for gastrointestinal side effects as the most common adverse effects 3

Absolute Contraindications

Do not use magnesium glycinate in children with: 1, 3

  • Severe renal impairment
  • Complete heart block or severe cardiac conduction abnormalities
  • Active gastrointestinal obstruction

Clinical Context

While emergency/acute care settings may use much higher IV magnesium doses (25-50 mg/kg for conditions like torsades de pointes or status asthmaticus), 4 these are distinct from chronic oral supplementation dosing. The 110-130 mg daily maximum applies specifically to routine oral supplementation in otherwise healthy children. 1

For comparison, research in 7-12 year-old children with ADHD used approximately 200 mg/day of elemental magnesium, 5 but this higher dose should only be considered under close medical supervision given the established gastrointestinal dose-limiting threshold of 110-130 mg for younger children. 1

References

Guideline

Maximum Daily Dose of Magnesium Bisglycinate for Children

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Magnesium and Melatonin Supplementation for Pediatric Sleep

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Magnesium Bisglycinate Supplementation in Children

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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