Treatment of Tongue Abscess
Immediate surgical drainage is the primary treatment for tongue abscess, combined with broad-spectrum intravenous antibiotics covering gram-positive, gram-negative, and anaerobic bacteria, with airway management as the critical priority. 1, 2
Airway Management Priority
- Tongue abscesses are potentially life-threatening due to airway compromise from tongue swelling and edema. 2, 3, 4
- Secure the airway immediately if the patient shows signs of respiratory distress, dyspnea, or significant tongue swelling. 4
- Be prepared for difficult intubation due to tongue anatomy and swelling; consider fiberoptic intubation or surgical airway if needed. 5, 4
- Transfer the patient to the operating room urgently if airway compromise is imminent or present. 2, 4
Surgical Drainage Approach
Two surgical techniques are available, with needle aspiration being increasingly preferred for uncomplicated cases:
Needle Aspiration (Preferred Initial Approach)
- Large-bore needle aspiration through the inferior surface of the tongue is effective and avoids exacerbating tongue edema. 6
- This technique provides immediate symptom relief and diagnostic confirmation while minimizing airway risk. 3, 6
- Aspiration can be performed under local anesthesia in cooperative patients with smaller abscesses. 3, 6
Incision and Drainage (Traditional Approach)
- Formal incision and drainage under general anesthesia is indicated for large abscesses, failed needle aspiration, or when airway control is already necessary. 2, 4
- Drain approximately 30mL or more of purulent material and irrigate the cavity with normal saline and 2% hydrogen peroxide. 2
- This approach requires general anesthesia with secured airway, increasing procedural risk but ensuring complete drainage. 2, 4
Antibiotic Therapy
Start broad-spectrum intravenous antibiotics immediately covering mixed oral flora:
- Ampicillin-sulbactam or cefoxitin are first-line agents due to coverage of gram-positive, gram-negative, and anaerobic bacteria from oral mucosa. 1
- Alternative regimens include clindamycin (covers anaerobes and most oral flora) or combination therapy with a beta-lactam plus metronidazole. 5, 2
- If MRSA is suspected (prior MRSA infection, injection drug use, or severe systemic infection), add vancomycin IV. 1, 7
- Continue IV antibiotics for an average of 5-6 days postoperatively, then transition to oral therapy based on clinical improvement. 1
Diagnostic Workup
- CT imaging of the oral cavity and pharynx is essential for diagnosis, determining abscess size and location, and planning surgical approach. 4
- Send aspirated pus for aerobic and anaerobic cultures to guide targeted antibiotic therapy. 5, 1
- Obtain blood cultures in all patients, as bacteremia occurs in up to 28% of deep space infections. 5
- Consult ear-nose-throat and maxillofacial surgery for evaluation of dental or gum infection as the source. 1
Critical Pitfalls to Avoid
- Never delay surgical drainage—delayed intervention significantly worsens outcomes and increases risk of airway loss. 1
- Do not rely on antibiotics alone; source control through drainage is mandatory. 1, 2
- Avoid incision through the dorsal tongue surface when possible, as this exacerbates edema and airway compromise. 6
- Do not perform lumbar puncture if meningeal signs are present, as this is contraindicated in space-occupying lesions. 5
Follow-Up and Monitoring
- Re-evaluate at 48-72 hours to ensure adequate drainage and clinical improvement. 1, 7
- Persistent fever, worsening swelling, or failure to improve indicates inadequate drainage requiring repeat imaging and possible re-drainage. 1
- Patients can typically be discharged 1 day after cessation of IV antibiotics if clinically stable. 1
- Monitor for complications including deeper spread to submandibular or parapharyngeal spaces, which would require more extensive surgical intervention. 4
Special Considerations
- Tongue abscesses are rare due to the tongue's rich vascular supply, extensive lymphatic drainage, and saliva's immunologic properties. 2, 8
- Consider immunocompromised states (diabetes, HIV, immunosuppressive therapy) as predisposing factors requiring more aggressive management. 3
- Posterior tongue (base of tongue) abscesses are more dangerous than anterior abscesses due to greater airway compromise risk and require more aggressive surgical approach. 4