What is the dosing frequency of Ferrlecit (Sodium Ferric Gluconate)?

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From the FDA Drug Label

Ferrlecit was given to both dose groups in eight divided doses during sequential dialysis sessions (a period of 16 to 17 days). The dosing frequency of Ferrlecit (Sodium Ferric Gluconate) is once per dialysis session, with a total of 8 divided doses administered over a period of 16 to 17 days 1.

From the Research

Dosing Frequency of Ferrlecit (Sodium Ferric Gluconate)

  • The dosing frequency of Ferrlecit (Sodium Ferric Gluconate) varies depending on the patient's condition and the study protocol 2, 3, 4, 5, 6.
  • In one study, sodium ferric gluconate complex was administered once per week intravenously over 10 minutes at the end of the dialysis session 2.
  • Another study used a dosing strategy of 62.5 mg/dose for children < 40 kg and 125 mg/dose for children > 40 kg, infused on eight consecutive hemodialysis runs 4.
  • A study compared the effects of two i.v. iron formulations, including sodium ferric gluconate, and found that maintenance doses of 62.5 mg were administered every two weeks if the serum ferritin concentration was 100-499 ng/mL and the transferrin saturation was 20-29% 5.
  • A clinical trial administered sodium ferric gluconate complex in sucrose over 8 consecutive dialysis days in equally divided doses to a total of either 0.5 or 1.0 g 6.

References

Research

[Iron replacement in hemodialysis patients with a normal serum ferritin level].

Deutsche medizinische Wochenschrift (1946), 2004

Research

Comparison of serum ferritin and transferrin saturation values associated with two i.v. iron formulations in hemodialysis patients.

American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2009

Research

Sodium ferric gluconate complex in sucrose is safe and effective in hemodialysis patients: North American Clinical Trial.

American journal of kidney diseases : the official journal of the National Kidney Foundation, 1999

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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