What are the proper care and maintenance procedures for a nephrostomy tube?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: December 24, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Nephrostomy Tube Care and Maintenance

Nephrostomy tubes should be routinely flushed with normal saline solution using 40-60 mL volumes, as this is the standard irrigation fluid that prevents hemolysis, hyponatremia, and electrolyte abnormalities that occur with non-isotonic solutions. 1, 2

Standard Flushing Protocol

Primary Flushing Technique

  • Use normal saline exclusively for all routine flushing and continuous irrigation during procedures 1, 2
  • Flush with 40-60 mL of warm water or normal saline as the initial approach 2
  • The syringe must aspirate and flush with ease; any resistance indicates tube obstruction or malposition requiring immediate evaluation 2
  • Proper flushing technique is more critical than the addition of heparin 2

Frequency of Maintenance

  • Flush regularly when tubes are not in continuous use to maintain patency 2
  • For tubes accessed infrequently, increase flushing intervals to prevent occlusion 2
  • Heparinized solutions may be used as a lock solution only when tubes remain closed for more than 8 hours, though the concentration of heparin is less important than adequate saline flushing 2

Tube Securement and Positioning

Fixation Methods

  • Secure tubes to the skin with sutures to prevent dislodgement, which occurs in approximately 11% of cases without proper reinforcement 3, 4
  • Consider using a rubber drainage tube (approximately 2 cm long, sheared longitudinally) as an outer casing sutured to the skin, which significantly reduces dislodgement rates to 0% versus 7-10% with conventional methods at 2-4 weeks follow-up 3

Monitoring During Care

  • Monitor for pain, swelling, or inability to flush during routine maintenance 2
  • Position patients upright during flushing attempts to minimize aspiration risk 2

Managing Tube Occlusion

Stepwise Approach to Clearing Obstructions

  1. First-line intervention: Attempt flushing with 40-60 mL of warm water using gentle pressure, which clears approximately one-third of obstructions 2
  2. Second-line intervention: If warm water fails, use an alkaline solution of pancreatic enzymes, which demonstrates a 96% success rate in clearing formula-related clogs and can clear an additional 50% of occluded tubes 2
  3. Third-line intervention: Reserve mechanical devices for cases where enzymatic treatment fails 2
  4. Last resort: Consider tube replacement only after all other methods have failed 2

Infection Management

Routine Monitoring

  • Asymptomatic bacteriuria is common and should not be treated in well-appearing patients 5
  • In the presence of infectious symptoms (fever, flank pain, systemic signs), treat similarly to complicated cystitis or pyelonephritis with broad-spectrum antibiotics 5

Special Considerations for Fungal Infections

  • For fungal urinary tract infections with nephrostomy tubes in place, perform irrigation with amphotericin B deoxycholate in conjunction with systemic antifungal therapy 2
  • Consider removal or replacement of the nephrostomy tube if feasible when treating fungal infections 2

Emergency Management of Purulent Drainage

  • If purulent urine is encountered, establish drainage immediately and administer broad-spectrum antibiotics 2
  • Sepsis is the most serious complication, occurring in 2-3% of cases and potentially contributing to death if drainage is not promptly established 6
  • Failed instrumentation with delay to definitive renal drainage is the most common factor associated with septic complications 6

Hemorrhage Management

Expected vs. Concerning Bleeding

  • Mild hematuria is present in approximately 50% of patients after nephrostomy tube placement and is expected 1
  • Gross hematuria is common immediately following catheter placement 5
  • Concerning findings: Prolonged hematuria or return of hematuria after previous resolution should trigger investigation for hematoma formation or delayed vascular injury 5

Management of Significant Bleeding

  • Clinically significant bleeding occurs in less than 1-4% of cases 1, 6, 4
  • Most hemorrhage cases settle with prolonged tube drainage alone without surgical intervention 6
  • Persistent bleeding requires arteriographic evaluation for pseudoaneurysms, fistulas, or frank extravasation, which can usually be treated with transcatheter embolization 1

Tube Removal Timing

Post-Procedure Drainage Duration

  • Most complex stones require nephrostomy tube drainage for at least 24 to 48 hours 1
  • Post-procedure tube management varies: some remove immediately, some within 24-48 hours, and some at 5-7 days depending on case complexity 1
  • Critical warning: Premature nephrostomy tube removal after percutaneous nephrostolithotomy results in prolonged hospitalization and marked patient discomfort 7

Optional Tube Placement Scenarios

  • In patients undergoing uncomplicated percutaneous nephrolithotomy who are presumed stone-free, placement of a nephrostomy tube is optional 1
  • The tubeless approach should not be undertaken if there is active hemorrhage or if another percutaneous procedure will likely be needed to remove residual stones 1

When to Seek Urgent Consultation

Indications for Advanced Imaging and Specialty Consultation

  • Suspected tube dislodgement or migration causing obstructive symptoms 5
  • Signs of serious infection with immune compromise or worsening renal function 5
  • Persistent or recurrent hemorrhage after initial resolution 5
  • Inability to flush tube despite troubleshooting measures 2
  • Suspected pleural injury (pneumothorax, which occurs more commonly with upper-pole calyceal puncture) 1

Laboratory and Imaging Requirements

  • Obtain laboratory testing and advanced imaging (ultrasound or CT) when serious complications are suspected 5
  • Ensure normal coagulation studies before any tube manipulation in high-risk patients 6

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Nephrostomy Tube Management

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Approach to nephrostomy tubes in the emergency department.

The American journal of emergency medicine, 2021

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.