Nephrostomy Tube Care and Maintenance
Nephrostomy tubes should be routinely flushed with normal saline solution using 40-60 mL volumes, as this is the standard irrigation fluid that prevents hemolysis, hyponatremia, and electrolyte abnormalities that occur with non-isotonic solutions. 1, 2
Standard Flushing Protocol
Primary Flushing Technique
- Use normal saline exclusively for all routine flushing and continuous irrigation during procedures 1, 2
- Flush with 40-60 mL of warm water or normal saline as the initial approach 2
- The syringe must aspirate and flush with ease; any resistance indicates tube obstruction or malposition requiring immediate evaluation 2
- Proper flushing technique is more critical than the addition of heparin 2
Frequency of Maintenance
- Flush regularly when tubes are not in continuous use to maintain patency 2
- For tubes accessed infrequently, increase flushing intervals to prevent occlusion 2
- Heparinized solutions may be used as a lock solution only when tubes remain closed for more than 8 hours, though the concentration of heparin is less important than adequate saline flushing 2
Tube Securement and Positioning
Fixation Methods
- Secure tubes to the skin with sutures to prevent dislodgement, which occurs in approximately 11% of cases without proper reinforcement 3, 4
- Consider using a rubber drainage tube (approximately 2 cm long, sheared longitudinally) as an outer casing sutured to the skin, which significantly reduces dislodgement rates to 0% versus 7-10% with conventional methods at 2-4 weeks follow-up 3
Monitoring During Care
- Monitor for pain, swelling, or inability to flush during routine maintenance 2
- Position patients upright during flushing attempts to minimize aspiration risk 2
Managing Tube Occlusion
Stepwise Approach to Clearing Obstructions
- First-line intervention: Attempt flushing with 40-60 mL of warm water using gentle pressure, which clears approximately one-third of obstructions 2
- Second-line intervention: If warm water fails, use an alkaline solution of pancreatic enzymes, which demonstrates a 96% success rate in clearing formula-related clogs and can clear an additional 50% of occluded tubes 2
- Third-line intervention: Reserve mechanical devices for cases where enzymatic treatment fails 2
- Last resort: Consider tube replacement only after all other methods have failed 2
Infection Management
Routine Monitoring
- Asymptomatic bacteriuria is common and should not be treated in well-appearing patients 5
- In the presence of infectious symptoms (fever, flank pain, systemic signs), treat similarly to complicated cystitis or pyelonephritis with broad-spectrum antibiotics 5
Special Considerations for Fungal Infections
- For fungal urinary tract infections with nephrostomy tubes in place, perform irrigation with amphotericin B deoxycholate in conjunction with systemic antifungal therapy 2
- Consider removal or replacement of the nephrostomy tube if feasible when treating fungal infections 2
Emergency Management of Purulent Drainage
- If purulent urine is encountered, establish drainage immediately and administer broad-spectrum antibiotics 2
- Sepsis is the most serious complication, occurring in 2-3% of cases and potentially contributing to death if drainage is not promptly established 6
- Failed instrumentation with delay to definitive renal drainage is the most common factor associated with septic complications 6
Hemorrhage Management
Expected vs. Concerning Bleeding
- Mild hematuria is present in approximately 50% of patients after nephrostomy tube placement and is expected 1
- Gross hematuria is common immediately following catheter placement 5
- Concerning findings: Prolonged hematuria or return of hematuria after previous resolution should trigger investigation for hematoma formation or delayed vascular injury 5
Management of Significant Bleeding
- Clinically significant bleeding occurs in less than 1-4% of cases 1, 6, 4
- Most hemorrhage cases settle with prolonged tube drainage alone without surgical intervention 6
- Persistent bleeding requires arteriographic evaluation for pseudoaneurysms, fistulas, or frank extravasation, which can usually be treated with transcatheter embolization 1
Tube Removal Timing
Post-Procedure Drainage Duration
- Most complex stones require nephrostomy tube drainage for at least 24 to 48 hours 1
- Post-procedure tube management varies: some remove immediately, some within 24-48 hours, and some at 5-7 days depending on case complexity 1
- Critical warning: Premature nephrostomy tube removal after percutaneous nephrostolithotomy results in prolonged hospitalization and marked patient discomfort 7
Optional Tube Placement Scenarios
- In patients undergoing uncomplicated percutaneous nephrolithotomy who are presumed stone-free, placement of a nephrostomy tube is optional 1
- The tubeless approach should not be undertaken if there is active hemorrhage or if another percutaneous procedure will likely be needed to remove residual stones 1
When to Seek Urgent Consultation
Indications for Advanced Imaging and Specialty Consultation
- Suspected tube dislodgement or migration causing obstructive symptoms 5
- Signs of serious infection with immune compromise or worsening renal function 5
- Persistent or recurrent hemorrhage after initial resolution 5
- Inability to flush tube despite troubleshooting measures 2
- Suspected pleural injury (pneumothorax, which occurs more commonly with upper-pole calyceal puncture) 1