How to manage PEG (Percutaneous Endoscopic Gastrostomy) tube oozing?

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Last updated: December 24, 2025View editorial policy

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Management of PEG Tube Oozing

For PEG tube leakage, immediately protect the surrounding skin with a hydrocolloid wafer as a keyhole dressing or apply a barrier cream containing zinc oxide, while addressing the underlying cause of the leakage. 1

Immediate Skin Protection Measures

  • Apply a hydrocolloid wafer as a keyhole dressing around the tube site to protect skin from gastric contents and absorb exudate 1
  • Use a topical skin barrier film or cream containing zinc oxide to prevent chemical irritation and skin breakdown 1
  • Apply a powdered absorbing agent if significant moisture is present 1
  • Clean the affected skin at least once daily using an antimicrobial cleanser 1

Identify and Address the Underlying Cause

Check Tube Positioning and Tension

  • Verify the external fixation plate allows at least 5 mm of free movement to prevent pressure necrosis while maintaining adequate tension 1
  • Push the tube approximately 2-3 cm ventrally and carefully pull it back to the resistance of the internal fixation flange to ensure proper positioning 2
  • Ensure the incision at the puncture site is sufficiently large (approximately 8 mm) to prevent pressure-related complications 2

Assess for Excessive Granulation Tissue

  • Excessive granulation tissue is vascular, bleeds easily, and commonly causes leakage around PEG tubes 1
  • Apply silver nitrate cauterization directly onto overgranulation tissue as first-line treatment 1
  • Alternatively, use a topical corticosteroid cream or ointment for 7-10 days combined with a foam dressing to provide compression 1
  • Apply a topical antimicrobial agent under the fixation device or use a foam or silver dressing over the affected area, changing only when significant exudate is present (minimum weekly) 1
  • If these measures fail, consider surgical removal or argon plasma coagulation 1

Rule Out Infection

  • Inspect the site daily for signs of infection: erythema >5 mm around the stoma, purulent discharge, or fever 1
  • Take a swab for microbiological examination if infection is suspected 1
  • Apply topical antimicrobial agents and perform daily sterile dressing changes for peristomal infections 1
  • Add systemic broad-spectrum antibiotics if topical treatment fails to resolve the infection 1
  • If infection cannot be resolved with combined topical and systemic antibiotics, remove the tube 1

Optimize Tube Care to Prevent Ongoing Leakage

  • Use a Y-compress under the tube to avoid formation of a moist cavity under the external fixation plate 1, 2
  • Maintain proper tension between internal and external fixation plates, checking regularly to prevent tissue ischemia or excessive leakage 2
  • Loosen and rotate the gastrostomy tube weekly to prevent mucosal overgrowth 3
  • Remove dressings before washing, rinse away residual soap, and dry the tube well before applying a new dressing 1

When Conservative Measures Fail

  • If all measures fail to control leakage, consider placing a new gastrostomy at a different location 1
  • For persistent gastrocutaneous fistula leakage after tube removal, combined electrochemical cautery and endoscopic clip placement has shown 82% complete closure rates in elderly patients 4
  • Consider tube replacement if there is evidence of tube degradation, breakage, or structural compromise 1

Common Pitfalls to Avoid

  • Do not overtighten the external fixation plate against the skin, as this causes pressure necrosis and paradoxically worsens leakage 1, 2
  • Avoid using noninvasive ventilation in the early postoperative period (first few days) after PEG placement, as abdominal distention can cause pressure necrosis and tube dislodgement 5
  • Recognize that minor redness (<5 mm) around the stoma is common and largely induced by movement, not necessarily infection 1
  • Transient leakage in the initial days after placement is common and often resolves with conservative management 1

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Management of High PEG Tube Residuals

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

PEG Tube Management Guidelines

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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