Treatment of an Abscessed Tooth
Surgical intervention—either root canal therapy for salvageable teeth or extraction for non-restorable teeth—is the definitive first-line treatment for a dental abscess, with antibiotics reserved only for patients with systemic involvement (fever, malaise, lymphadenopathy) or those who are medically compromised. 1, 2
Primary Treatment Algorithm
Immediate surgical management is mandatory and includes:
- Root canal therapy for teeth that are restorable, periodontally sound, with adequate crown structure remaining for post-endodontic restoration 1
- Extraction for non-restorable teeth due to extensive caries, severe crown destruction, structural compromise, severe periodontal disease, or failed previous endodontic treatment 1, 2
- Incision and drainage for accessible abscesses with fluctuant swelling 1, 2
Critical point: Adding antibiotics to proper surgical management shows no statistically significant differences in pain or swelling outcomes—surgery alone is sufficient for most cases 1, 2
When Antibiotics Are Indicated
Antibiotics should be added to surgical treatment only when:
- Systemic involvement is present: fever, malaise, or lymphadenopathy 1, 2
- Patient is medically compromised or immunocompromised 1, 2
- Infection extends into facial spaces or cervicofacial tissues 1, 2
- Diffuse swelling that cannot be effectively drained 1
- Failure to respond to surgical treatment alone after 48-72 hours 3
Antibiotic Selection (When Indicated)
First-line regimen:
- Amoxicillin 500 mg three times daily for 5 days in combination with surgical management 3, 2
- Alternative: Phenoxymethylpenicillin for patients with systemic involvement 2
Second-line regimen (for treatment failure or enhanced anaerobic coverage):
- Amoxicillin-clavulanate 875/125 mg twice daily for 5-7 days 3
For penicillin allergy:
- Clindamycin 300-450 mg three times daily 3
- Doxycycline can be considered as an alternative in adults 2
Common Pitfalls to Avoid
Never prescribe antibiotics without surgical intervention—this is ineffective, does not eliminate the source of infection, and contributes to antibiotic resistance 1, 2, 4
Do not delay surgical treatment in favor of antibiotic therapy alone, as the infection will not resolve and will become progressively worse, potentially leading to airway obstruction and septicemia 4
Antibiotics should not be used for irreversible pulpitis, chronic periodontitis, or peri-implantitis 2
When to Escalate Care
Immediate referral to oral surgeon or emergency department is required for:
- Signs of deep space involvement: trismus, floor of mouth elevation, dysphagia, or respiratory compromise 3
- Spreading infection or systemic illness despite appropriate initial management 3
- Persistent symptoms after 48-72 hours of proper surgical and antibiotic treatment 3
For severe cases requiring hospitalization:
- IV antibiotics: Clindamycin 600-900 mg IV every 6-8 hours or piperacillin-tazobactam 3.375g IV every 6 hours 3
- Consider CT imaging to evaluate for deep space abscess or complications 3