What is the recommended ECG (electrocardiogram) setting in mm/mV (millimeters per millivolt)?

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Standard ECG Calibration Settings

The standard ECG calibration is 10 mm/mV (1 mV = 10 mm), which means each small box (1 mm) represents 0.1 mV and each large box (5 mm) represents 0.5 mV. 1

Technical Specifications

Amplitude Calibration

  • Standard gain setting: 10 mm/mV is universally recommended for routine ECG recordings 1
  • At this standardization, 1 mV produces a 10 mm deflection on the ECG paper 1
  • Each small box (1 mm) = 0.1 mV 1
  • Each large box (5 mm) = 0.5 mV 1

When to Adjust Calibration

  • Half-standard (5 mm/mV): Use when QRS complexes are too tall and exceed the recording boundaries, preventing accurate measurement 1
  • Double-standard (20 mm/mV): Use when QRS voltages are very low and difficult to measure accurately at standard calibration 1
  • Always document when non-standard calibration is used, as this affects voltage-based diagnostic criteria (e.g., left ventricular hypertrophy) 1

Critical Technical Requirements

Frequency Response Settings

  • High-frequency cutoff: minimum 150 Hz for adults and adolescents 1
  • High-frequency cutoff: 250 Hz for infants and children to capture rapid deflections accurately 1
  • Low-frequency cutoff: 0.05 Hz for routine filters, or relaxed to 0.67 Hz for linear digital filters with zero phase distortion 1
  • Inadequate high-frequency response systematically underestimates QRS amplitude and smooths important features like Q waves 1

Digital Sampling Requirements

  • Minimum sampling rate: 500 samples per second to allow accurate 150 Hz filtering and reduce amplitude measurement errors to <1% 1
  • A/D conversion: minimum 12-bit precision for adequate signal resolution 1
  • Higher sampling rates (1200 Hz) are preferred for capturing high-frequency components accurately 2

Common Pitfalls to Avoid

Calibration Errors

  • Never use 40 Hz high-frequency cutoff for diagnostic ECGs—this invalidates all amplitude measurements used for diagnostic classification 1
  • Electrocardiographs should automatically alert users when suboptimal settings are used 1
  • Verify that voltage calibration is accurate to ±2% 1

Measurement Accuracy

  • Use the largest-amplitude deflection in each lead as representative of that measurement, per ANSI/AAMI standards 1
  • Noise levels should be reduced to <1 µV (root mean square) in the averaged signal for time-domain analysis 1
  • Ensure proper electrode placement and skin preparation to minimize baseline wander and electrical interference 2

Documentation Requirements

  • Always document if non-standard calibration (5 mm/mV or 20 mm/mV) is used 1
  • Specify which diagnostic criteria are applied, as voltage-based criteria (e.g., Sokolow-Lyon, Cornell voltage for LVH) are calibration-dependent 1
  • Computer interpretations require physician verification—automated systems still produce frequent errors 2

Age-Specific Considerations

  • Adults >35 years: Standard 10 mm/mV calibration with 150 Hz high-frequency cutoff 1
  • Adolescents (16-35 years): Standard calibration but recognize that voltage criteria for LVH have lower accuracy in this age group 1
  • Children and infants: Standard 10 mm/mV calibration but require 250 Hz high-frequency cutoff to capture rapid deflections 1

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

EKG Interpretation Guidelines

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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