Treatment of Bell's Palsy
Start oral corticosteroids immediately within 72 hours of symptom onset—this is the only proven effective treatment that significantly improves recovery rates from 63.6% to 83% at 3 months and from 81.6% to 94.4% at 9 months. 1, 2
Primary Treatment: Corticosteroids (First-Line, Mandatory)
Prescribe one of these regimens for all patients 16 years and older: 1, 2
- Prednisolone 50 mg daily for 10 days (preferred regimen), OR
- Prednisone 60 mg daily for 5 days, followed by a 5-day taper (10 mg reduction daily) 1, 2
Critical timing: Treatment must begin within 72 hours of symptom onset—delaying beyond this window significantly reduces effectiveness. 1, 2
Special populations requiring individualized assessment: 2
- Diabetes mellitus
- Morbid obesity
- Previous steroid intolerance
- Pregnancy (though treatment is still recommended with careful benefit-risk discussion) 1
Antiviral Therapy: Optional Add-On Only
Never prescribe antivirals alone—they are completely ineffective as monotherapy. 1, 2 The landmark 2007 New England Journal of Medicine trial definitively showed no benefit of acyclovir alone (71.2% recovery vs 75.7% without acyclovir, p=0.50). 3
You may offer combination therapy (antivirals + corticosteroids) within 72 hours as an option: 1, 2
- Valacyclovir 1 g three times daily for 7 days, OR 4, 5
- Acyclovir 400 mg five times daily for 10 days 1, 4
The added benefit is minimal—some studies suggest modest improvement in reducing synkinesis (abnormal facial muscle co-contraction), but corticosteroids remain the cornerstone. 1, 4, 6 One 2003 study showed 87.5% complete recovery with combination therapy versus 68% with no treatment, but this compared against untreated controls, not corticosteroids alone. 5
Eye Protection: Mandatory and Immediate
Implement aggressive eye protection immediately for all patients with impaired eye closure to prevent permanent corneal damage. 1, 2
- Lubricating ophthalmic drops every 1-2 hours while awake
- Sunglasses outdoors to protect against wind and foreign particles
Nighttime protection (critical): 1, 2
- Ophthalmic ointment at bedtime for sustained moisture
- Eye patching or taping (with careful instruction on proper technique to avoid corneal abrasion)
- Moisture chambers using polyethylene covers for severe cases
Urgent ophthalmology referral required for: 1, 2
- Severe impairment with complete inability to close the eye
- Eye pain, vision changes, redness, discharge, or foreign body sensation
- Any signs of corneal exposure or damage
For persistent lagophthalmos beyond 3 months, surgical options include: 1
- Tarsorrhaphy (temporary or permanent partial eyelid closure)
- Eyelid weight implantation
- Botulinum toxin injections
Pediatric Considerations
Children have better prognosis than adults with spontaneous recovery rates up to 90%. 2, 4 However, the evidence for corticosteroid benefit in children is inconclusive—no high-quality pediatric-specific trials exist. 1
- Consider oral corticosteroids on a case-by-case basis with substantial caregiver involvement in shared decision-making
- If treating, use prednisolone 1 mg/kg/day (maximum 50-60 mg) for 5 days followed by a 5-day taper
- Emphasize to families that most children recover completely without treatment
Follow-Up and Reassessment
Mandatory reassessment or specialist referral is required for: 1, 2, 7
- Incomplete facial recovery at 3 months after symptom onset
- New or worsening neurologic findings at any point
- Development of ocular symptoms at any point
Expected recovery timeline: 1, 7
- Most patients begin showing recovery within 2-3 weeks
- Complete recovery typically occurs within 3-4 months
- 70% of patients with complete paralysis recover fully within 6 months
- Patients with incomplete paralysis have recovery rates up to 94%
At 3 months, refer to: 1
- Facial nerve specialist or facial plastic surgeon for reconstructive options
- Ophthalmologist for persistent eye closure problems
- Mental health specialist for psychological support (depression risk is elevated)
Therapies NOT Recommended
Do not prescribe or recommend: 1, 2
- Antiviral monotherapy (completely ineffective) 1, 2, 3
- Surgical decompression (rarely indicated except in specialized cases) 1, 2
- Acupuncture (poor-quality trials, indeterminate benefit-harm ratio) 1
- Physical therapy (limited evidence, though may help with severe paralysis and developing synkinesis) 1, 4
Diagnostic Testing: What NOT to Do
Do not order routine laboratory testing or imaging for typical Bell's palsy. 1 Diagnosis is clinical, based on acute unilateral facial weakness involving the forehead with onset under 72 hours and no identifiable cause. 1
Order MRI with and without contrast only for atypical features: 1
- Second paralysis on the same side
- Isolated branch paralysis
- Other cranial nerve involvement
- No recovery after 3 months
- Worsening symptoms
Electrodiagnostic testing (ENoG/EMG): 1
- May offer to patients with complete facial paralysis (not incomplete)
- Most reliable when performed 3-14 days post-onset
- Greater than 10% nerve response amplitude indicates excellent prognosis
- Less than 10% function carries up to 50% risk of incomplete recovery
Common Pitfalls to Avoid
Critical errors that worsen outcomes: 1, 2
- Delaying corticosteroids beyond 72 hours (significantly reduces effectiveness)
- Prescribing antivirals alone (completely ineffective, delays appropriate treatment)
- Inadequate eye protection (leads to permanent corneal damage)
- Failing to refer at 3 months for incomplete recovery (delays access to reconstructive options and psychological support)
- Improper eye taping technique (can cause corneal abrasion—patients need careful instruction)
- Missing atypical features (requires imaging and specialist evaluation to exclude tumor, stroke, Lyme disease, or trauma) 1, 6