From the Research
The best time to take lithium orotate is typically with meals, either in the morning or evening, depending on your personal response, as this can help reduce potential stomach upset and improve absorption, as suggested by the most recent and highest quality study available 1. When considering the timing of lithium orotate intake, it's essential to prioritize minimizing side effects and maximizing absorption. Taking it with food can help achieve this, and the specific timing can be adjusted based on individual response, such as taking it in the evening if drowsiness occurs.
- For mood stabilization, consistent timing each day is crucial to maintain steady blood levels.
- Unlike prescription lithium carbonate, lithium orotate is typically taken at lower doses (often 5-20mg of elemental lithium per day) and doesn't require blood monitoring, though consulting with a healthcare provider before starting is still recommended 2.
- Staying well-hydrated throughout the day is important when taking any form of lithium, as dehydration can increase lithium concentration in the body, potentially leading to adverse effects such as tremor, excessive thirst, or frequent urination, as noted in studies on lithium side effects and toxicity 3, 2.
- If side effects occur, adjusting the timing or discussing with a healthcare provider may be necessary to find an optimal regimen that balances efficacy with tolerability, considering the latest understanding of lithium's effects on mortality and metabolite profiles 4.