What is the treatment for an ingrown toenail?

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Treatment of Ingrown Toenails

Start with conservative medical management using twice-daily antiseptic soaks combined with topical corticosteroids, and reserve surgical intervention for cases that fail to improve after 2-4 weeks or present with severe infection. 1, 2, 3

Initial Conservative Management for Mild Cases

Antiseptic Soaking Protocol

  • Perform antiseptic soaks twice daily for 10-15 minutes using either dilute vinegar (50:50 dilution with water) or 2% povidone-iodine solution 1, 3
  • Povidone-iodine 2% is the most evidence-based first-line antiseptic agent according to the American Academy of Dermatology 2

Anti-Inflammatory Treatment

  • Immediately after each soak, apply a mid- to high-potency topical corticosteroid ointment to the affected nail fold twice daily to reduce local inflammation 1, 3
  • Do not use topical steroids if purulent drainage is present 2

Mechanical Relief Techniques

  • Insert cotton wisps or dental floss under the ingrown lateral nail edge to separate it from the underlying inflamed tissue 1, 3, 4
  • Alternatively, place a plastic tube with a lengthwise incision (gutter splint) on the lateral nail edge to encapsulate it 1, 5
  • Tape the lateral nail fold away from the nail plate to reduce pressure 2, 3

Management of Infected Ingrown Toenails

When to Add Antibiotics

  • Do not routinely prescribe antibiotics for mild ingrown toenails unless clear signs of infection are present, such as purulent drainage or localized cellulitis with significant erythema extending beyond the nail fold 3
  • If pus is present, obtain cultures before initiating antibiotics 1
  • For mild-to-moderate infections, prescribe cephalexin or amoxicillin-clavulanate for 1-2 weeks targeting Staphylococcus aureus and gram-positive organisms 2, 3
  • Up to 25% of cases have bacterial or fungal superinfections involving both gram-positive and gram-negative organisms 2

Treatment-Refractory Cases

  • For recurrent, severe, or treatment-refractory cases after 2-4 weeks, consider oral doxycycline 100 mg twice daily with follow-up after one month 1, 3

Management of Granulation Tissue

  • If granulation tissue persists despite topical corticosteroids, consider scoop shave removal with hyfrecation or silver nitrate chemical cauterization 1
  • Add topical timolol 0.5% gel twice daily under occlusion as adjunctive therapy for persistent granulation tissue 1
  • For treatment-refractory cases, consider intralesional triamcinolone acetonide 1

When to Escalate to Surgical Intervention

Timing Criteria

  • Reassess after 2 weeks of conservative management; if persistent pain or drainage continues beyond 2-4 weeks despite appropriate therapy, escalate to surgical consultation 1, 3
  • Do not delay surgical intervention beyond 2 weeks if medical management fails 2

Immediate Surgical Indications

  • Severe infections with deep abscess, extensive tissue involvement, or substantial necrosis require immediate surgical consultation 2
  • Recurrent cases that have failed multiple conservative attempts warrant surgical management 2, 6

Surgical Options

  • Partial nail avulsion followed by either phenolization or direct surgical excision of the nail matrix are equally effective 4, 5
  • Partial nail avulsion combined with phenolization is more effective at preventing symptomatic recurrence compared to surgical excision without phenolization, though it carries a slightly increased risk of postoperative infection 4

Prevention of Recurrence

Patient Education Essentials

  • Trim toenails straight across and not too short 1, 3
  • Wear comfortable, well-fitting shoes and cotton socks to avoid repeated trauma 1, 3
  • Apply topical emollients daily to cuticles and periungual tissues to maintain skin barrier function 1, 3
  • Avoid cutting cuticles or manipulating the nail folds 1, 3
  • Wear protective gloves when working with water or chemicals 1, 3
  • Avoid artificial nails and harsh nail products 1
  • Maintain good hand hygiene 1

Post-Treatment Monitoring

  • Continue antiseptic soaks if inflammation persists after any intervention 1
  • Reassess wound healing at 2 weeks post-procedure to determine if additional interventions are needed 1
  • Monitor for signs of infection including increased pain, redness, swelling, or purulent drainage 1

Special Populations

Diabetic Patients

  • Provide more aggressive monitoring and prompt treatment by trained healthcare professionals, as ingrown toenails can progress to foot ulceration with significant morbidity in diabetics 3
  • Integrated foot care should be provided every 1-3 months for diabetic patients 3

References

Guideline

Medical Management of Ingrown Nails

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Treatment of Infected Ingrown Toenail

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Treatment of Mild Ingrown Toenail

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Management of the ingrown toenail.

American family physician, 2009

Research

Ingrown Toenail Management.

American family physician, 2019

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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