Triaging Chest Pain in Urgent Care
In urgent care, immediately obtain a 12-lead ECG within 10 minutes of patient arrival and transfer any patient with suspected acute coronary syndrome (ACS) or other life-threatening conditions to the emergency department by EMS—do not delay transfer for troponin testing or additional workup in the office setting. 1
Immediate Actions (First 10 Minutes)
ECG Acquisition
- Obtain and interpret a 12-lead ECG within 10 minutes for any patient presenting with chest pain where a noncardiac cause is not immediately evident 1
- If an ECG cannot be obtained in your urgent care facility, immediately transfer the patient to the ED so one can be performed 1
- The 10-minute window is critical for identifying STEMI and initiating timely reperfusion therapy 1, 2
Identify Life-Threatening Conditions
Focus on the "big three" plus additional emergencies 2, 3:
- Acute Coronary Syndrome (ACS): Retrosternal discomfort building gradually over minutes, radiating to left arm/neck/jaw, with dyspnea, nausea, or diaphoresis 2
- Acute Aortic Syndromes: Sudden-onset tearing/ripping pain radiating to the back 2
- Pulmonary Embolism: Sudden dyspnea with pleuritic chest pain, especially with risk factors 2
- Tension pneumothorax, esophageal perforation, cardiac tamponade 3
Critical History Elements
Pain Characteristics That Matter
High probability descriptors for ischemia 1:
- Pressure, dull, squeezing, aching, gripping, burning, heaviness, tightness
- Exertional or stress-related
- Retrosternal location
- Central or left-sided radiation
Low probability descriptors 1:
- Stabbing, sharp, fleeting, shifting
- Right-sided or pleuritic
- Reproduced by palpation
Essential Questions
- Exact location and radiation pattern: Pain radiating to right arm (OR 2.23), both arms (OR 2.69), or central chest (OR 3.29) significantly increases AMI likelihood 4
- Temporal features: Gradual onset over minutes suggests ACS; sudden ripping pain suggests aortic dissection 1, 2
- Associated symptoms: Vomiting (OR 3.50), observed sweating (OR 5.18) strongly predict AMI 4
- Precipitating factors: Exertion, stress, meals, breathing, position changes 2
- Risk factors: Age, sex, diabetes, hypertension, hyperlipidemia, smoking, family history of premature CAD 2
Physical Examination
Perform a focused cardiovascular examination to identify 1, 2:
- Diaphoresis, tachypnea, tachycardia, hypotension
- Crackles, S3 gallop, new murmurs
- Pulse differentials (aortic dissection)
- Unilateral absent breath sounds (pneumothorax)
- Pericardial friction rub (pericarditis)
- Costochondral tenderness (musculoskeletal)
Special Population Considerations
Women
- Women are at high risk for underdiagnosis of ACS 1, 2
- Emphasize accompanying symptoms more common in women: nausea, fatigue, dyspnea, arm pain, jaw pain, epigastric discomfort 1, 2
- Chest pain remains the dominant symptom in women with ACS, but accompanying symptoms may be more prominent 1
Older Adults (≥75 years)
- Consider ACS when atypical presentations occur 1, 2:
- Isolated shortness of breath
- Syncope or near-syncope
- Acute delirium or confusion
- Unexplained falls
- Classic chest pain may be absent 1
Transfer Decision Algorithm
IMMEDIATE EMS TRANSFER if any of the following 1:
- ECG shows STEMI or ischemic changes (ST-elevation, ST-depression, new T-wave inversions)
- Clinical evidence of ACS: Ongoing chest pain with high-risk features, hemodynamic instability, arrhythmias
- Suspected aortic dissection, PE, or other life-threatening condition
- ECG unavailable in your facility
Why EMS Transfer is Mandatory 1, 2:
- Allows prehospital ECG acquisition to facilitate reperfusion
- Trained personnel can provide treatment for chest pain, arrhythmias, and defibrillation en route
- Shorter travel time to ED
- Personal automobile transport is associated with increased risk and should be avoided 1
AVOID THIS CRITICAL ERROR 1:
Do NOT delay transfer to obtain troponin or perform additional diagnostic testing beyond the ECG in the urgent care setting when ACS is suspected—this delay can be detrimental to patient outcomes 1
If ECG is Nondiagnostic but Suspicion Remains
- Do not reassure and discharge based on a normal ECG alone 1, 2
- Transfer to ED for serial ECGs and troponin measurement 1
- High-sensitivity cardiac troponin is the most sensitive test for myocardial injury (sensitivity >90%, specificity >95%) and must be measured in the ED setting 2
Common Pitfalls to Avoid
- Do not use nitroglycerin response as a diagnostic tool—esophageal spasm and other conditions may also respond 2
- Do not assume young age excludes ACS—it can occur even in adolescents without traditional risk factors 2
- Do not dismiss sharp or pleuritic pain as non-cardiac—pericarditis and atypical ACS presentations can occur 2
- Do not rely on "typical" vs "atypical" terminology—the term "atypical" is misleading and discouraged; use "noncardiac" if heart disease is not suspected 1
- Do not assume rest pain or left arm radiation alone are diagnostic—these have limited diagnostic value (OR 0.67 and 1.36 respectively) 4
Low-Risk Patients Who May Be Managed Outpatient
Only after excluding life-threatening causes with ECG and clinical assessment 1, 2:
- Clear noncardiac etiology identified (e.g., costochondritis with reproducible tenderness, herpes zoster with dermatomal rash)
- Low-risk features by structured risk assessment
- Stable vital signs
- Normal or clearly noncardiac ECG
Use clinical decision pathways (HEART score, TIMI, GRACE) to systematically risk-stratify patients, though these are best applied in the ED setting with troponin availability 5