What are the complications of phacoemulsification (Phacoemulsification, a cataract surgery procedure)?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: February 13, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

From the Guidelines

Phacoemulsification complications include iris prolapse and posterior capsule rupture.

Common Complications

  • Iris prolapse
  • Posterior capsule rupture These complications are less common with phacoemulsification compared to manual extracapsular cataract extraction (ECCE) or manual small-incision cataract extraction (MSICS) 1.

Additional Considerations

Other potential complications and considerations in phacoemulsification include:

  • Cystoid macular edema (CME), which can be reduced with topical nonsteroidal anti-inflammatory drugs (NSAIDs) 1
  • Postoperative bacterial endophthalmitis, which can be reduced with intracameral antibiotic administration 1
  • Dry eye disease (DED), which can be a multifactorial and complex condition associated with cataract surgery, and asymptomatic DED is highly prevalent 1 To minimize these complications, considerations during surgery include:
  • Minimizing surgical duration and light exposure
  • Avoiding large corneal incisions and aspirating speculums
  • Keeping thermal energy of the phacoemulsification device low
  • Using periocular administration or intraocular injection of antibiotics and/or steroids immediately before the end of surgery 1

From the Research

Intraoperative Complications

  • Posterior capsule rupture is a common complication, occurring in 6.7% of cases 2, 9% of cases 3, and 18% of cases in patients with posterior polar cataract 4
  • Vitreous loss is another complication, occurring in 5.4% of cases 2 and 3.7% of cases in combined phacoemulsification and vitreoretinal surgery 5
  • Dislocated lenticular fragments can occur, with a frequency of 1.0% 2
  • Iatrogenic retinal hole is a complication, occurring in 5.3% of cases in combined phacoemulsification and vitreoretinal surgery 5
  • Transient corneal edema can occur, with a frequency of 3.2% in combined phacoemulsification and vitreoretinal surgery 5

Postoperative Complications

  • Posterior capsule opacification is a common complication, occurring in 21.5% of cases in combined phacoemulsification and vitreoretinal surgery 5 and 8% of cases in phacoemulsification after pars plana vitrectomy 3
  • Elevated intraocular pressure can occur, with a frequency of 9.7% in combined phacoemulsification and vitreoretinal surgery 5 and 7% of cases in phacoemulsification after pars plana vitrectomy 3
  • Macular edema can occur, with a frequency of 8.1% in combined phacoemulsification and vitreoretinal surgery 5
  • Retinal detachment can occur, with a frequency of 6% of cases in phacoemulsification after pars plana vitrectomy 3 and 3.2% of cases in combined phacoemulsification and vitreoretinal surgery 5
  • Vitreous hemorrhage can occur, with a frequency of 3.7% in combined phacoemulsification and vitreoretinal surgery 5

Risk Factors

  • Previous vitrectomy can increase the risk of complications during phacoemulsification, including posterior capsule rupture 3, 6
  • Posterior polar cataract can increase the risk of posterior capsule rupture during phacoemulsification 4
  • Hard nucleus cataract in a vitrectomized eye can increase the risk of posterior capsule rupture during phacoemulsification 6

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.