Hospital Admission Criteria for Adult Pneumonia
Adults with pneumonia should be hospitalized if they have a CURB-65 score ≥2, which corresponds to a mortality risk of 9.2% or higher and indicates need for active intervention. 1, 2, 3
Primary Assessment: CURB-65 Scoring System
The IDSA/ATS guidelines strongly recommend using CURB-65 as the primary tool for admission decisions because it directly measures illness severity rather than just mortality risk. 1, 2
CURB-65 Components (1 point each): 2
- Confusion (new onset)
- Uremia (BUN ≥20 mg/dL)
- Respiratory rate ≥30 breaths/min
- Blood pressure (systolic <90 mmHg or diastolic ≤60 mmHg)
- Age ≥65 years
Risk Stratification and Disposition: 2, 3
- Score 0-1: Mortality 0.7-2.1% → Consider outpatient treatment
- Score 2: Mortality 9.2% → Hospitalize or provide intensive home health services
- Score 3: Mortality 14.5% → Hospitalize and assess for ICU
- Score 4-5: Mortality 40-57% → Hospitalize and assess for ICU
Absolute Indications for Hospitalization (Regardless of CURB-65)
Physiologic Instability: 3
- Oxygen saturation <90-92% on room air or PaO₂ <60 mmHg
- Respiratory rate >30 breaths/min
- Systolic blood pressure <90 mmHg or diastolic <60 mmHg
- Septic shock or need for vasopressors
- Acute respiratory failure requiring intubation
Clinical Complications: 3
- Pleural effusion or empyema
- Multilobar involvement
- Metastatic infection
- Suspected bacteremia
Functional/Social Barriers: 1, 3, 4
- Inability to reliably take or tolerate oral medications
- Intractable vomiting
- Lack of adequate caregiver support or social resources
- Homelessness or psychiatric illness preventing adherence
- Immunocompromised status (HIV, immunosuppression)
- Moderate to severe COPD
- Heart failure
- Chronic renal or liver disease
- Active malignancy
- Functional asplenia
ICU Admission Criteria
Immediate ICU Admission Required: 1, 3
- Septic shock requiring vasopressors
- Acute respiratory failure requiring intubation and mechanical ventilation
ICU or High-Level Monitoring Unit When ≥3 Minor Criteria Present: 1, 3
- Respiratory rate ≥30 breaths/min
- PaO₂/FiO₂ ratio <250
- Multilobar infiltrates
- Confusion
- Blood urea nitrogen ≥20 mg/dL
- Leukopenia from infection (WBC <4,000/μL)
- Thrombocytopenia
- Hypothermia (temperature <36°C)
- Hypotension requiring aggressive fluid resuscitation
Critical Point: CURB-65 alone performs poorly for predicting ICU needs (sensitivity only 78.4% for critical care interventions). 5 Use the IDSA/ATS severe CAP criteria above for ICU triage decisions rather than relying solely on CURB-65 score. 2
Common Clinical Pitfalls to Avoid
Underestimation of Severity: 2, 3, 5
- Young patients (<65 years) with severe respiratory failure may have low CURB-65 scores despite critical illness—15.6% of patients with CURB-65 0-1 required ICU admission and 6.4% received critical care interventions 5
- Previously healthy patients can develop severe CAP requiring ICU care 1
- Approximately 27% of patients with CURB-65 score of 2 were admitted to ICU and 15.4% received critical care interventions 5
Delayed Recognition: 1
- Up to 45% of patients ultimately requiring ICU care are initially admitted to general medical floors 1
- Delayed transfer to ICU for respiratory failure or septic shock is associated with increased mortality 1
Over-reliance on Scoring Systems: 1, 3
- Objective scores must be supplemented with clinical judgment regarding ability to take oral medications and availability of support resources 1
- Approximately 7.5% of patients initially treated as outpatients require subsequent hospitalization within 10 days and have higher mortality risk 3
Mandatory Follow-Up for Outpatient Management
If treating as outpatient (CURB-65 0-1 only): 3, 4
- Clinical reassessment must be planned within 24-48 hours
- Patient must be able to reliably take oral medications
- Adequate caregiver support must be available
- Contact physician if no improvement within 3 days 2
When in doubt, hospitalize—the consequences of missed severe pneumonia far outweigh the costs of potentially unnecessary admission. 3