From the FDA Drug Label
The primary efficacy endpoint in the two studies that evaluated the effect of tadalafil for the signs and symptoms of BPH was the International Prostate Symptom Score (IPSS), a four week recall questionnaire that was administered at the beginning and end of a placebo run-in period and subsequently at follow-up visits after randomization The IPSS assesses the severity of irritative (frequency, urgency, nocturia) and obstructive symptoms (incomplete emptying, stopping and starting, weak stream, and pushing or straining), with scores ranging from 0 to 35; higher numeric scores representing greater severity
The answer to whether Cialis helps with urine retention is that it may help with the symptoms of Benign Prostatic Hyperplasia (BPH), which can include urine retention.
- Tadalafil has been shown to improve the International Prostate Symptom Score (IPSS), which includes symptoms such as incomplete emptying and weak stream.
- However, the effect of tadalafil on maximum urinary flow rate (Qmax) was not significantly different from placebo in the studies.
- Therefore, while tadalafil may help with some symptoms of BPH, its effect on urine retention specifically is not clearly established 1.
From the Research
Cialis (tadalafil) does not have a significant advantage in improving benign prostatic hyperplasia-related acute urinary retention versus tamsulosin alone, as shown in a randomized clinical trial 2.
Key Points to Consider
- The study found that the addition of tadalafil to α-blockers has no significant benefit in improving acute urinary retention compared to tamsulosin alone 2.
- However, other studies have shown that tadalafil can improve lower urinary tract symptoms suggestive of benign prostatic hyperplasia, including a significant increase in maximum urinary flow rate compared to placebo 3.
- Tadalafil works by relaxing the smooth muscle in the prostate and bladder, which can improve urine flow and reduce symptoms of urinary retention 4, 5.
- The typical dose for BPH symptoms is 5mg taken once daily at approximately the same time each day.
- Patients should notice improvement in urinary symptoms within 1-2 weeks of starting treatment.
- Side effects may include headache, indigestion, back pain, muscle aches, flushing, and nasal congestion.
- It's essential to consult with a healthcare provider before starting Cialis, especially if you have cardiovascular issues, as they can determine if it's appropriate for your specific situation.
Important Considerations
- Alpha-blockers, such as tamsulosin, may increase the success rate of trial without catheter (TWOC) in patients with acute urinary retention secondary to benign prostatic hyperplasia 6.
- The choice of medication should be based on individual patient needs and medical history.
- Regular follow-up with a healthcare provider is necessary to monitor the effectiveness of treatment and adjust as needed.