Does Manjaro (generic name not available) cause side effects, what are they?

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Dainyal Siddiqui, MD

Internal Medicine

Manuel Jimenez, MD

Cardiology

Franz Pierre-Louis, MD

Infectious Disease

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Last updated: April 9, 2025 • View editorial policy

From the Research

Monjaro (tirzepatide) can cause side effects, including nausea, vomiting, diarrhea, and abdominal pain, as reported in the most recent study 1. The side effects of Monjaro are primarily gastrointestinal in nature and may also include decreased appetite, constipation, upper abdominal discomfort, and injection site reactions.

Common side effects: + Nausea + Vomiting + Diarrhea + Decreased appetite + Constipation + Upper abdominal discomfort + Abdominal pain
Less common but more serious side effects: + Pancreatitis + Gallbladder problems + Hypoglycemia (especially when used with insulin or insulin secretagogues) + Potential thyroid tumors (based on animal studies) According to the study 1, the risk of side effects may increase with higher doses, which is why Monjaro treatment typically starts at a lower dose (2.5 mg once weekly) and gradually increases over time. If experiencing severe or persistent side effects, patients should contact their healthcare provider rather than discontinuing the medication abruptly, as most side effects are manageable with proper medical supervision and may be outweighed by the benefits of improved blood sugar control and potential weight loss for those with type 2 diabetes 1.

References

Research

New Drug: Tirzepatide (Mounjaro™).

The Senior care pharmacist, 2023

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This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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