Recommended Ointments for Wound Dressing
For clean superficial wounds and abrasions, use plain petrolatum or petrolatum-based ointments under an occlusive dressing; antibiotic ointments are not necessary and do not improve healing outcomes. 1
General Wound Care Approach
Clean Superficial Wounds and Abrasions
- Use occlusive dressings with petrolatum-based products (such as plain petrolatum, hydrogel, or film dressings) to maintain a moist wound healing environment 1
- Avoid routine use of antibiotic ointments - there is no evidence that antibiotic or antibacterial dressings improve wound healing or decrease infection rates in clean wounds 1
- Plain petrolatum is preferred over antibiotic-containing ointments because it avoids the risk of allergic contact dermatitis and antibiotic resistance without compromising healing 2
Thermal Burns (Partial-Thickness)
For small partial-thickness burns managed at home, after cooling, apply petrolatum, petrolatum-based antibiotic ointment (such as polymyxin), honey, or aloe vera with a clean nonadherent dressing. 1
- Petrolatum-based products (with or without antibiotics like polymyxin) have been shown to improve healing time in partial-thickness burns 1
- Triple-antibiotic ointment enhances reepithelialization and reduces scarring compared to silver-based dressings 3, 4
- Honey and aloe vera are acceptable alternatives 1
- Avoid silver sulfadiazine for routine first aid - while FDA-approved for burns 5, antibiotic ointments demonstrate superior healing rates and less scarring in comparative studies 3, 4
Diabetes-Related Foot Ulcers
Do not use topical antiseptic, antimicrobial dressings, honey, collagen, or alginate dressings for diabetic foot ulcers - use basic dressings that absorb exudate and maintain a moist wound healing environment. 1
- No specific dressing type has been shown superior to simple gauze dressings for healing diabetic foot ulcers 1
- Heavy exudate wounds need moisture-absorbing dressings; dry wounds need moisture-adding treatments 1
- The only exception: consider sucrose-octasulfate impregnated dressing for non-infected, neuro-ischemic ulcers that fail standard care after 2 weeks 1
Key Clinical Pitfalls
Avoid These Common Mistakes:
- Do not use povidone-iodine for wound cleansing - it provides no benefit over tap water or saline irrigation 1
- Do not apply antibiotic ointments to diabetic foot ulcers - strong evidence shows no benefit 1
- Do not use Aquaphor Healing Ointment if concerned about wound redness - it causes higher incidence of wound redness (52%) compared to plain petrolatum (12%) 6
- Recognize allergic contact dermatitis risk with antibiotic ointments, particularly those containing neomycin 7, 2
When to Escalate Care:
- Animal or human bite wounds require immediate medical facility evaluation regardless of topical treatment 1
- Signs of infection (redness, swelling, foul drainage, increased pain, fever) warrant dressing removal, wound inspection, and medical care 1
- Burns involving face, hands, feet, genitals, or >10% body surface area (5% in children) require specialized burn center treatment 1
Practical Algorithm
For routine wound dressing selection:
- Clean wound thoroughly with tap water or sterile saline (not antiseptics) 1
- For clean superficial wounds: Apply plain petrolatum and occlusive dressing 1
- For small partial-thickness burns: Apply petrolatum-based antibiotic ointment (e.g., bacitracin/polymyxin) or plain petrolatum with nonadherent dressing 1, 7
- For diabetic foot ulcers: Use basic moisture-balancing dressings only; no topical antimicrobials 1
- Change dressings at least daily for infected wounds to allow examination 1