From the Guidelines
Dextromethorphan can cause several side effects, ranging from mild to severe, including drowsiness, dizziness, nausea, and mild stomach discomfort, as well as more serious effects like hallucinations and dissociative effects at higher doses, as reported in various studies 1.
Common Side Effects
- Drowsiness
- Dizziness
- Nausea
- Mild stomach discomfort
- Confusion
- Excitability
- Nervousness
- Restlessness
Serious Side Effects
- Hallucinations
- Impaired coordination
- Slurred speech
- Dissociative effects similar to those of ketamine
Interactions with Other Medications
Dextromethorphan can interact with certain medications, particularly MAO inhibitors and SSRIs, potentially causing serotonin syndrome, a dangerous condition characterized by high fever, confusion, irregular heartbeat, and seizures 1.
Recommended Dosage
The recommended dosage of dextromethorphan is 10-15 mg tid or qid, with a maximum dose of 120 mg/d, as indicated in the study by Molassiotis et al. 1.
Conclusion is not allowed, so the answer will be based on the information provided and the question asked.
It is essential to stick to the recommended dosage and consult a healthcare provider if experiencing concerning side effects or taking other medications that might interact with dextromethorphan, as reported in the studies 1.
From the Research
Side Effects of Dextromethorphan
The side effects of Dextromethorphan are generally infrequent and not severe, but can include:
- Neurological disturbances
- Cardiovascular disturbances
- Gastrointestinal disturbances These symptoms are usually dose-related, as indicated by the study published in 1992 2.
Safety Concerns
Particular safety concerns arise when: