Prohilo Treatment Protocol for Skin Rejuvenation
I cannot provide a specific protocol for "Prohilo" as this product name does not appear in the available evidence, and no FDA drug label or guideline specifically addresses this formulation.
What the Evidence Actually Addresses
The provided evidence focuses exclusively on autologous platelet concentrates (APCs) including PRP and PRF for skin rejuvenation 1, not hyaluronic acid products. While hyaluronic acid (HA) is mentioned in the research literature as effective for skin rejuvenation 2, 3, the guidelines provided do not establish treatment protocols for HA-based products like what "Prohilo" may represent.
If You Are Referring to Profhilo (Hyaluronic Acid)
If "Prohilo" is actually "Profhilo" (a stabilized hyaluronic acid product), the available evidence is limited to one research study on acne scars, not general skin rejuvenation 4. This study used:
- 1 cc of Profhilo per treatment session 4
- Two treatment sessions spaced 1 month apart 4
- Administered via intradermal injection 4
However, this protocol was specifically for acne scar treatment combined with subcision, not standalone skin rejuvenation 4.
General Hyaluronic Acid Principles (Not Product-Specific)
Based on research evidence for HA-based treatments:
- HA works through multiple mechanisms: soft tissue augmentation, improved skin hydration, collagen and elastin stimulation, and volume restoration 2
- HA is naturally occurring in skin with negligible immunologic risk 3
- HA can be rapidly reversed with hyaluronidase injection 3
- Duration of effect may exceed expected bioavailability due to collagen synthesis and fibroblast stimulation 3
Critical Gap in Evidence
Without manufacturer-specific protocols, FDA labeling, or clinical guidelines for the specific product you're asking about, I cannot provide a definitive treatment protocol. The evidence provided focuses on platelet-rich therapies, not hyaluronic acid monotherapy for rejuvenation.
What You Should Do
- Consult the manufacturer's prescribing information for the specific product
- Verify the exact product name (Prohilo vs. Profhilo vs. another HA formulation)
- Follow FDA-approved labeling if available for your jurisdiction