Treatment for Swelling and Burning
For acute swelling and burning from thermal burns, immediately cool the affected area with clean running water for 5-20 minutes, then apply petrolatum-based antibiotic ointment and cover with a clean, non-adherent dressing. 1, 2, 3
Immediate First-Line Management (First 20 Minutes)
Cooling Phase
- Apply clean running water for 5-20 minutes to limit tissue damage and reduce both pain and swelling 4, 1, 2
- Use water temperature between 15-25°C (room temperature or cool tap water) 4
- Never apply ice directly to the affected area, as this causes additional tissue damage and can worsen outcomes 4, 1, 2
- Monitor for hypothermia in children during prolonged cooling, especially with larger affected areas 1, 2
Concurrent Actions During Cooling
- Remove any jewelry from the affected area before swelling progresses to prevent vascular compromise 1, 2
- Administer over-the-counter analgesics (acetaminophen or NSAIDs) for pain control 4, 1, 3
Topical Treatment After Cooling
First-Line Topical Agent
- Apply petrolatum-based antibiotic ointment (such as triple antibiotic ointment containing bacitracin, neomycin sulfate, and polymyxin B) as the preferred first-line treatment 1, 3
- This promotes faster reepithelialization and reduces scar formation compared to alternatives 3
- Apply a thin layer to the entire affected area 3
Alternative Topical Options
- Honey may be used and shows benefit for infection resolution with reduced healing time (7.8 days faster than silver sulfadiazine) 3
- Aloe vera is reasonable for small burns managed at home 3
- Plain petrolatum without antibiotics is acceptable if antibiotic ointment is unavailable 1, 3
Dressing Application
- Cover with a clean, non-adherent dressing after applying topical treatment 1, 2, 3
- Change dressing daily or as needed 3
Critical Pitfalls to Avoid
- Do NOT use silver sulfadiazine (Silvadene) as first-line therapy—it delays healing and worsens scarring compared to petrolatum-based treatments 1, 3
- Do NOT apply butter, oil, or home remedies to burns, as these can exacerbate injury 1, 2, 3
- Do NOT break intact blisters, as this significantly increases infection risk 1, 3
- Do NOT use ice directly on burns 4, 1, 2
When to Seek Immediate Medical Attention
High-Risk Anatomic Locations
- Burns involving face, hands, feet, or genitals require specialized burn center evaluation regardless of size, due to high risk of functional disability and cosmetic deformity 1, 2, 3
Severity Indicators
- Burns covering >10% body surface area in adults (>5% in children) 1
- Signs of inhalation injury (soot around nose/mouth, difficulty breathing) 1, 2, 3
- Circumferential burns or blue/purple/pale extremities indicating vascular compromise 3
- Signs of infection: increasing pain, redness, swelling, or purulent discharge 2
Special Considerations
For Erythromelalgia (Chronic Burning/Swelling)
If symptoms represent erythromelalgia rather than acute thermal injury, the approach differs significantly:
- Avoid prolonged ice or cold water immersion (limit to 10 minutes, 4 times daily maximum) to prevent tissue damage, ulceration, and "immersion foot" 4
- Elevate extremities during symptom flares 4
- Consider topical treatments as first-line therapy before systemic medications 4
- Aspirin is first-line systemic therapy, particularly for secondary erythromelalgia from myeloproliferative disease 4