What are the physical exam findings suggestive of cellulitis?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: April 9, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

From the Guidelines

Physical exam findings suggestive of cellulitis include erythema, warmth, swelling, and tenderness of the affected skin area, with poorly defined borders that may expand over time, as well as pain, shiny or taut skin due to edema, and potential systemic signs such as fever, chills, and malaise 1. These findings are crucial for diagnosing cellulitis, a common bacterial skin infection.

  • Key physical exam findings include:
    • Erythema (redness)
    • Warmth
    • Swelling
    • Tenderness
    • Poorly defined borders
    • Pain
    • Shiny or taut skin due to edema
  • Systemic signs may include:
    • Fever
    • Chills
    • Malaise
  • It is essential to monitor the progression or improvement of cellulitis by marking the borders of erythema and checking for fluctuance, which may indicate abscess formation 1.
  • Cellulitis can occur anywhere on the body, but it most commonly affects the lower extremities, and identifying potential entry points like wounds, ulcers, or dermatitis can help determine the cause 1.
  • The presence of crepitus on palpation raises concern for necrotizing fasciitis or gas gangrene, which are surgical emergencies 1.

From the Research

Physical Exam Findings for Cellulitis

The physical exam findings that suggest cellulitis include:

  • Expanding erythema 2, 3, 4, 5
  • Warmth 2, 3, 4, 5
  • Tenderness 2, 3, 4, 5
  • Swelling 2, 3, 4, 5
  • Pain 5

Clinical Presentation

Cellulitis typically presents with an acute onset of these symptoms, making it a clinical diagnosis based on history and physical examination 2, 3, 4, 5. However, it can be difficult to diagnose due to various infectious and non-infectious clinical mimickers such as venous stasis dermatitis, contact dermatitis, eczema, lymphedema, and erythema migrans 3, 5, 6.

Diagnostic Challenges

Microbiological diagnosis is often unobtainable due to poor sensitivity of culture specimens 5, and there are no effective diagnostic modalities, making the diagnosis of cellulitis primarily based on history and physical examination 2.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Cellulitis: A Review.

JAMA, 2016

Research

Cellulitis: diagnosis and management.

Dermatologic therapy, 2011

Research

Cellulitis.

Infectious disease clinics of North America, 2021

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.