What is the proper treatment for burns?

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Last updated: December 28, 2025View editorial policy

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Burn Treatment

Immediately cool the burn with clean running water for 5-20 minutes, then apply petrolatum-based antibiotic ointment and cover with a non-adherent dressing. 1, 2

Immediate First Aid (Within First 30 Minutes)

Cooling Protocol

  • Apply clean running water at room temperature (15°C to 25°C) for 5-20 minutes as soon as possible after injury to reduce pain, depth of injury, and need for skin grafting 3, 1, 2
  • Start cooling within 30 minutes of injury for maximum benefit 3
  • Monitor children closely during cooling for signs of hypothermia, especially with burns >10% total body surface area (TBSA) 3, 1
  • Adults with TBSA <20% and children with TBSA <10% should be cooled in the absence of shock 3

Critical Actions During Cooling

  • Remove jewelry and constrictive items immediately before swelling occurs to prevent vascular compromise 1, 4
  • Remove contaminated clothing if not stuck to the skin 5

Wound Care After Cooling

Cleaning

  • Cleanse the wound with tap water, isotonic saline, or antiseptic solution 3, 4

Blister Management

  • Leave burn blisters intact - this improves healing and reduces pain 3
  • If epidermis is already detached, leave it in place to act as a biological dressing 4

Topical Treatment

  • Apply petrolatum-based antibiotic ointment (such as triple antibiotic containing bacitracin, neomycin sulfate, and polymyxin B) as first-line treatment 1, 2
  • Apply a thin layer and cover with clean, non-adherent dressing 1, 2
  • Change dressing daily or as needed 2
  • Avoid silver sulfadiazine for superficial burns as it delays healing and worsens scarring 3, 1, 2

Alternative Topical Agents

  • Honey may be used and shows reduced healing time (7.8 days faster than silver sulfadiazine) with less hypertrophic scarring 2
  • Aloe vera is reasonable for small burns managed at home 2

Pain Management

  • Administer over-the-counter analgesics such as acetaminophen or NSAIDs after cooling 1, 2, 4
  • For severe pain during dressing changes, consider titrated intravenous ketamine combined with other analgesics 3
  • Non-pharmacological techniques (virtual reality, hypnosis) may be combined with medications when appropriate 3

Fluid Resuscitation for Extensive Burns

  • Administer 20 mL/kg of intravenous crystalloid solution within the first hour for adults with burns ≥20% TBSA and children with ≥10% TBSA 4
  • Use balanced crystalloid solutions, preferably Ringer's Lactate 4

When to Seek Specialized Burn Center Care

Immediate Transfer Required For:

  • Burns involving face, hands, feet, or genitalia regardless of size - high risk of functional disability and cosmetic deformity 1, 2, 4
  • Burns >10% TBSA in adults or >5% TBSA in children 1, 4
  • Signs of inhalation injury (soot around nose/mouth, difficulty breathing) 1, 2, 4
  • Circumferential burns 2
  • Blue, purple, or pale extremities indicating vascular compromise 2

Critical Pitfalls to Avoid

Never Do These:

  • Do not apply ice or ice water - this increases tissue damage and can cause cold injury 3, 1, 2, 4, 6
  • Do not apply butter, oil, or home remedies - these exacerbate injury 1, 2, 4
  • Do not break or pop intact blisters - significantly increases infection risk 1, 2, 4
  • Do not use silver sulfadiazine as first-line therapy on superficial burns - delays healing 3, 1, 2
  • Do not apply oil-based emollients near nostrils in patients on oxygen therapy due to combustion risk 1

Antibiotic Prophylaxis

  • Routine systemic antibiotic prophylaxis is not recommended for burn patients 3
  • Apply topical antimicrobials only to areas with necrotic tissue, not the entire burn surface 4

Ongoing Monitoring

  • Reevaluate dressings daily 3, 4
  • Monitor for signs of infection (increased pain, redness, swelling, discharge) 4
  • Continue treatment until satisfactory healing occurs or the burn site is ready for grafting 7

References

Guideline

Management of Second-Degree Burns

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Management of Open Partial-Thickness Burns

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Management of Scalds and Burns

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Chemical burn to the skin: A systematic review of first aid impacts on clinical outcomes.

Burns : journal of the International Society for Burn Injuries, 2022

Research

Cold injury complicating burn therapy.

The Journal of trauma, 1985

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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