What are the key assessments and recommendations for a newborn's 2-week checkup?

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Newborn 2-Week Checkup: Key Assessments and Recommendations

All newborns should be examined at 3-5 days after hospital discharge, with specific timing based on when they left the hospital: 72 hours for discharge before 24 hours, 96 hours for discharge between 24-47.9 hours, and 120 hours for discharge between 48-72 hours. 1, 2, 3

Growth and Physical Assessment

Weight and hydration status are mandatory assessments at the 2-week visit:

  • Measure actual weight and calculate percentage change from birth weight 2, 3
  • Plot weight, length, and head circumference on appropriate growth charts 2
  • Assess hydration through physical examination, feeding patterns, and documentation of stool/urine output frequency 2, 3
  • Perform complete head-to-toe examination including assessment of tone, posture, primitive reflexes, and spontaneous movements 2

Specific physical examination components include:

  • Umbilical cord assessment for signs of infection, bleeding, or delayed separation 2, 3
  • Skin examination for any abnormalities 2
  • General appearance and vital signs 3
  • Genitalia examination 3

Jaundice Evaluation

Do not rely on visual inspection alone for jaundice assessment—objective measurement is mandatory if any doubt exists about severity, particularly in darkly pigmented infants. 1, 2, 3

  • Measure total serum bilirubin (TSB) or transcutaneous bilirubin (TcB) if jaundice is present 1, 2, 3
  • Interpret bilirubin levels according to the infant's age in hours, not days 2
  • For elevated bilirubin, obtain blood type, Coombs' test, complete blood count, and smear 2

Critical red flag: Any jaundice persisting beyond 3 weeks requires:

  • Measurement of total and direct/conjugated bilirubin to identify cholestasis 1, 2, 3
  • Verification of newborn thyroid and galactosemia screening results 1, 2, 3
  • Blood typing and Coombs test if not previously done 3
  • Follow-up until complete resolution 3

Feeding Assessment

Breastfeeding mothers should be advised to nurse at least 8-12 times per day during the first several days. 1

  • Assess adequacy of intake through feeding patterns and weight gain 1, 2
  • Document voiding and stooling patterns 1
  • Provide support for breastfeeding difficulties 1
  • Do not routinely supplement non-dehydrated breastfed infants with water or dextrose water 1

Laboratory and Screening Review

Review all newborn screening results if available:

  • Confirm newborn metabolic screening results 2, 3
  • Verify hearing screening completion 3
  • Ensure all state-mandated screenings are complete 3

For NICU graduates, note that screening timing differs:

  • Initial screening on day of birth prior to interventions 3
  • Repeat screening at 1 and/or 2 weeks of life 3

Blood Type and Antibody Testing

Prenatal maternal blood work should be reviewed:

  • All pregnant women should have been tested for ABO and Rh(D) blood types with serum screen for unusual isoimmune antibodies 1
  • If mother is Rh-negative or prenatal grouping unavailable, obtain direct antibody test (Coombs'), blood type, and Rh(D) type on infant's cord blood 1
  • If maternal blood is group O, Rh-positive, cord blood testing is optional but surveillance and follow-up must be appropriate 1

Parent Education and Follow-Up

Provide written and verbal information including:

  • Explanation of jaundice and how to monitor for it 1
  • Signs requiring immediate medical attention 1
  • Feeding guidance and expectations 1

Schedule next visit according to standard periodicity:

  • Follow-up at 1 month, then 2,4,6,9, and 12 months of age 2, 3

Common Pitfalls to Avoid

  • Never estimate jaundice severity by visual inspection alone—this leads to errors, especially in darkly pigmented infants 1, 2
  • Do not interpret bilirubin levels without considering the infant's age in hours—this can lead to misdiagnosis 2
  • Do not discharge infants with inadequate follow-up plans—if appropriate follow-up cannot be ensured in the presence of elevated risk for hyperbilirubinemia, delay discharge until follow-up is secured or the period of greatest risk (72-96 hours) has passed 1
  • Do not miss prolonged jaundice beyond 3 weeks—this requires evaluation for cholestasis and other serious conditions 1, 2, 3

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Newborn Check-up Recommendations

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Newborn Checkup Schedule

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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