What are the recommended vaccinations and assessments for a 4-month well-child checkup?

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Last updated: December 28, 2025View editorial policy

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4-Month Well-Child Checkup

At the 4-month well-child visit, administer the second doses of DTaP, Hib, PCV, IPV, and rotavirus vaccines, along with the third dose of hepatitis B if using a combination vaccine. 1, 2

Core Vaccinations at 4 Months

The following vaccines should be administered at this visit:

Standard Immunization Series

  • DTaP (Diphtheria, Tetanus, acellular Pertussis): Second dose of the primary series 1, 2, 3
  • Hib (Haemophilus influenzae type b): Second dose; note that if PRP-OMP formulation (PedvaxHIB or ComVax) was used at 2 months, this dose is still required, but the 6-month dose will not be needed 1, 2
  • PCV (Pneumococcal Conjugate Vaccine): Second dose of the primary series 1, 2
  • IPV (Inactivated Poliovirus): Second dose 1, 2, 3
  • Rotavirus vaccine: Second dose; must be administered by 8 months of age, with the series not to be initiated after 14 weeks 6 days of age 1, 2, 4

Hepatitis B Considerations

  • Hepatitis B vaccine: If using combination vaccines containing HepB (such as DTaP-IPV-HB-PRP-T hexavalent), a dose at 4 months is permissible as part of a 4-dose series 1
  • If monovalent HepB was used for previous doses, no dose is needed at 4 months; the third dose should be given at 6-18 months 1, 2

Developmental and Health Assessments

Growth Monitoring

  • Measure weight, length, and head circumference and plot on growth charts 5
  • Assess growth trajectory from previous visits 5

Developmental Surveillance

  • Perform developmental surveillance at this visit, though formal developmental screening tools are reserved for 9,18, and 30-month visits 5
  • Observe for age-appropriate milestones including social smiling, head control, and visual tracking 5

Maternal Mental Health

  • Screen for postpartum depression in mothers, as this is recommended for infants up to 6 months of age 5

Anticipatory Guidance

Feeding Recommendations

  • Breastfeeding: Encourage exclusive breastfeeding through 6 months, as cessation before 6 months is associated with childhood obesity 5
  • Solid foods: Advise against introduction before 6 months of age, as early transition is associated with childhood obesity 5
  • Juice avoidance: Counsel that juice should be avoided before 1 year of age 5

Safety Counseling

  • Car seat positioning: Ensure car seat remains rear-facing until at least 2 years of age or until height/weight limit for the seat is reached 5
  • Safe sleep practices: Review safe sleep guidelines including supine positioning and avoiding soft bedding

Dental Health

  • Discuss fluoride supplementation if water supply is not fluoridated 5
  • Counsel on oral hygiene practices even before tooth eruption 5

Common Pitfalls to Avoid

Vaccine Timing Errors

  • Do not delay rotavirus vaccination beyond the maximum age constraints, as the final dose must be completed by 32 weeks of age 1
  • Ensure minimum 4-week intervals between doses have been maintained from the 2-month visit 2

Combination Vaccine Confusion

  • When using hexavalent vaccines (DTaP-IPV-HB-PRP-T), recognize that this creates a 4-dose hepatitis B series rather than the standard 3-dose series 1, 6
  • If PRP-OMP Hib vaccine was used at 2 months, document this to avoid unnecessary 6-month Hib dose 1

Missed Screening Opportunities

  • Do not overlook maternal postpartum depression screening, as this visit represents one of the last opportunities within the recommended screening window 5

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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