From the Research
Abilify (aripiprazole) is not typically associated with acute kidney injury (AKI), and the risk of AKI with aripiprazole is not significantly higher compared to other antipsychotics, as shown in a study published in 2017 1. While all medications have potential side effects, AKI is not a commonly reported adverse effect of Abilify. The medication primarily works on dopamine and serotonin receptors in the brain and is used to treat conditions like schizophrenia, bipolar disorder, and depression. Some key points to consider:
- Abilify's most common side effects include weight gain, restlessness, headache, and gastrointestinal symptoms.
- If you're taking Abilify and experiencing symptoms that might suggest kidney problems (such as decreased urination, swelling in legs or feet, or fatigue), you should contact your healthcare provider immediately.
- These symptoms could be related to other causes or medications.
- Patients with pre-existing kidney disease or those taking multiple medications should be particularly vigilant about monitoring kidney function through regular blood tests.
- Always discuss any concerns about medication side effects with your healthcare provider rather than stopping medication on your own. A study published in 2023 2 highlights the importance of timely and accurate identification of AKI and understanding its pathophysiological mechanisms, but it does not specifically mention Abilify as a cause of AKI. Another study from 2017 3 actually suggests that aripiprazole may have nephroprotective effects, potentially through the involvement of nitric oxide, which could further support the notion that Abilify is not typically associated with AKI.