From the Research
Role of Coenzyme Q10 in Treating Muscle Fatigue
- Coenzyme Q10 (CoQ10) is a popular nutritional supplement that has been studied for its potential role in reducing muscle fatigue 1, 2, 3, 4, 5.
- Research suggests that CoQ10 supplementation may be beneficial in reducing fatigue symptoms, particularly in individuals with statin-related fatigue and fibromyalgia 2, 3.
- A meta-analysis of 13 randomized controlled trials found that CoQ10 supplementation resulted in a statistically significant reduction in fatigue scores compared to placebo groups 2.
- The effectiveness of CoQ10 supplementation in reducing fatigue may be correlated with the daily dose and treatment duration, with higher doses and longer treatment durations resulting in greater fatigue reduction 2.
- CoQ10 may also have performance-enhancing effects during repeated bouts of supramaximal exercises, and may be used as an ergogenic aid 4.
- Additionally, CoQ10 supplementation has been shown to improve high-intensity interval exercise performance by reducing oxidative stress and muscle damage in swimmers 5.
- The potential mechanisms by which CoQ10 exerts its effects on muscle fatigue include its antioxidant properties, which help to reduce oxidative stress and inflammation, and its role in the mitochondrial electron transport chain, which helps to generate energy for muscle contractions 1, 2, 3, 4, 5.