What is the cause of persistent pharyngeal swelling and fever for 10 days?

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Differential Diagnosis for Throat Swelling and Fever

Single Most Likely Diagnosis

  • Pharyngitis: This is the most common cause of throat swelling and fever, often due to viral or bacterial infections, with streptococcal pharyngitis being a prominent bacterial cause. The duration of 10 days could suggest a bacterial etiology, but viral pharyngitis can also last this long.

Other Likely Diagnoses

  • Tonsillitis: Inflammation of the tonsils, which can be caused by viral or bacterial pathogens, leading to throat swelling and fever.
  • Peritonsillar Abscess: A complication of tonsillitis where an abscess forms beside the tonsils, causing severe throat pain, swelling, and fever.
  • Mononucleosis (Infectious Mononucleosis): Caused by Epstein-Barr virus, it can lead to fever, sore throat, and swollen lymph nodes, which might be perceived as throat swelling.

Do Not Miss Diagnoses

  • Epiglottitis: A potentially life-threatening condition that causes inflammation of the epiglottis, which can lead to airway obstruction. It presents with severe throat pain, fever, and difficulty swallowing.
  • Retropharyngeal Abscess: An abscess in the tissues in the back of the throat, which can cause throat swelling, fever, and potentially life-threatening airway obstruction.
  • Lemierre's Syndrome: A rare but serious condition following a bacterial pharyngitis, characterized by fever, throat pain, and swollen lymph nodes, which can progress to sepsis and thrombophlebitis of the internal jugular vein.

Rare Diagnoses

  • Diphtheria: A bacterial infection affecting the membranes of the throat and nose, though rare in areas with widespread vaccination, it can cause throat swelling and fever.
  • Angioedema: A condition characterized by the rapid swelling of the dermis, subcutaneous tissue, mucosa, and submucosal tissues, which can involve the throat and cause significant airway compromise.
  • Thyroiditis: Inflammation of the thyroid gland, which can cause throat swelling and fever, though it is less commonly associated with these symptoms compared to other diagnoses.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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