What area is likely to develop paresthesia in a patient (Pt) with back pain radiating to the leg and inability to perform dorsiflexion?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: December 30, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Dorsal Foot and Great Toe Paresthesia

The patient will most likely develop paresthesia in the dorsal aspect of the foot and the big toe, as this presentation of back pain radiating to the leg with inability to dorsiflex indicates L5 nerve root compression, typically from an L5-S1 disc lesion. 1

Neuroanatomical Localization

The clinical presentation described—back pain with leg radiation and loss of dorsiflexion—points specifically to L5 nerve root pathology:

  • The L5 nerve root innervates the dorsal aspect of the foot, including the big toe, making sensory loss in this area the characteristic finding for L5 compression. 1
  • L5-S1 disc lesions typically compress the L5 nerve root as it exits the neural foramen, producing this specific pattern of neurological deficits. 1
  • Foot dorsiflexion and great toe extension are controlled by the L5 nerve root, which aligns with the motor deficit described in this patient. 1, 2

Distinguishing from Other Nerve Root Patterns

It's important to differentiate this from adjacent nerve root compressions:

  • S1 nerve root compression produces lateral foot paresthesia and affects plantar flexion (not dorsiflexion), along with loss of ankle jerk reflex. 2, 3
  • L4 nerve root pathology affects the medial thigh and knee strength, not foot dorsiflexion. 2
  • The inability to dorsiflex specifically excludes S1 pathology, as plantar flexion is primarily controlled by S1, not L5. 1

Clinical Caveat About Dermatomal Patterns

While the dorsal foot and great toe are the expected areas for L5 paresthesia, be aware of significant individual variation:

  • Research shows that only 13.3% of patients with surgically proven L5 nerve root compression recorded sensory symptoms on both anterior and posterior L5 dermatome areas. 4
  • For pins and needles specifically, only 20.9% of L5 compression patients recorded more than 50% of their symptoms within the classic L5 dermatome. 4
  • Despite this variation, the dorsal foot and great toe remain the most reliable clinical indicators for L5 pathology when combined with dorsiflexion weakness. 1

Diagnostic Confirmation

To confirm the diagnosis and localize the lesion:

  • MRI of the lumbar spine is the preferred imaging modality, providing superior definition of nerve root pathology at the L5-S1 level. 1, 2
  • Electrodiagnostic studies should be performed to differentiate radiculopathy from plexopathy or peripheral nerve lesions. 1, 2
  • The combination of motor deficit (dorsiflexion weakness) with sensory symptoms in the dorsal foot distribution provides strong clinical evidence for L5 radiculopathy. 1, 3

References

Guideline

L5-S1 Disc Lesion Neurological Effects

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Lateral Thigh Sensation and Nerve Root Pathology

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Sciatic Nerve Formation and Clinical Significance

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Related Questions

What is the appropriate management for a 40-year-old female presenting with paresthesia (tingling sensation) in the upper limb?
What are the causes of paresthesia (abnormal sensations such as tingling or numbness) in both upper limbs?
What is the evaluation and treatment approach for a patient presenting with onset of left leg paresthesia, without other neurological findings, back pain, or injury?
What is the approach to a 28-year-old man presenting with right leg pain following a traumatic explosion?
What is the best approach to evaluate and manage a 33-year-old male with left arm paresthesias, no chest pain, and no shortness of breath, with a possible mechanical cause related to sleep position, and no known cardiac or pulmonary history?
What is the significance of persistent cytogenetic abnormalities in a patient with trilineage dysplasia in sustained clinical remission on azacitidine (Aza) + venetoclax (Ven)?
Should hypomagnesemia be corrected before hypocalcemia when both coexist?
What is the diagnosis and management for a patient with type 1 diabetes mellitus (DM) and chronic kidney disease (CKD) presenting with fever, flank pain, impaired renal function, and signs of infection?
After hip surgery, a patient has lost sensation in the anterior thigh, what other area can be expected to also have lost sensation?
What is the recommended evaluation and management for a patient presenting with dizziness, bilateral lower limb weakness, and blurred vision?
What is the recommended dosage of dobutamine (inodilator) for decompensated heart failure?

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.